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Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Platelet-rich plasma injections can effectively treat stubborn alopecia areata.

Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.

Finasteride effectively treats hirsutism in women, but more research needed for long-term results.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

Different diagnostic criteria greatly affect PCOS diagnosis rates in teenagers.

PCOS is a long-term condition that needs more research for better understanding and treatment.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

Indian women with PCOS may need different ultrasound criteria for diagnosis than current standards.

The document concludes that proper diagnosis and individualized treatment are crucial for managing androgenization in women effectively.

PCOS is common in young women, especially those aged 21-30, and often involves symptoms like irregular periods, weight gain, and acne.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

Women with PCOS have more Bifidobacterium in their gut compared to those without PCOS.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.