May 2008 in “The International Conference on Mathematics and Engineering Physics” This study reports that combining low level laser treatment with liposome-delivered methylene blue may effectively target sebaceous glands in mice, with efficacy influenced by laser timing and drug absorption.
10 citations
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September 1997 in “Molecular carcinogenesis” This study found that mirex and TPA promote papilloma formation in CD-1 mouse skin through distinct populations of mutant Ha-ras cells, resulting in additive tumor yields.
3 citations
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October 2024 in “Veterinary Medicine and Science” This study reported successful treatment of sarcoptic mange in two wild bare-nosed wombats using three topical doses of moxidectin, clearing skin crusting and mites within two weeks.
March 2021 in “Berkala Ilmu Kesehatan Kulit dan Kelamin” This review discusses the treatment options for male androgenetic alopecia, including FDA-approved therapies and new possibilities, but reports no new clinical results.
November 2024 in “Journal of Cosmetic Dermatology” This study found that valproic acid-loaded microemulsion formulations enhanced skin penetration pathways in guinea pigs compared to an aqueous solution, with composition elements like oil content and surfactant ratios significantly affecting drug delivery performance.
108 citations
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August 2017 in “Clinical, Cosmetic and Investigational Dermatology” This review highlights microneedling's promise as an adjuvant therapy for enhanced drug delivery in dermatology, especially for conditions like atrophic scars and pigmentation disorders, though its efficacy for vitiligo is limited.
April 2016 in “Journal of the American Academy of Dermatology”
July 2020 in “IP International Journal of Maxillofacial Imaging/International journal of maxillofacial imaging/IP International journal of maxillofacial imaging” The authors concluded that mesotherapy is a new, effective, and safer dermatologic treatment option for conditions like alopecia, skin rejuvenation, and hyperpigmentation due to its efficiency and reduced treatment time.
March 2025 in “Asian Journal of Beauty and Cosmetology” This study found that microspicule cosmetics with low-molecular-weight peptide complexes significantly improved skin whitening, pore condition, and skin barrier function over four weeks compared to a non-microspicule formulation.
14 citations
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October 2024 in “Nano Convergence” This study found that an injectable hydrogel dressing with silver nanoparticles showed promise in healing MRSA-infected wounds by reducing inflammation, supporting tissue regeneration, and maintaining prolonged antibacterial activity, highlighting its potential as an effective treatment strategy.
41 citations
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September 2017 in “Advanced Healthcare Materials” This study found that the DexIEME hydrogel promotes complete skin regeneration and scar attenuation in murine and porcine models, suggesting potential for treating deep dermal injuries.
19 citations
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January 2023 in “ACS Omega” This study developed sodium alginate and epigallocatechin gallate cryogels cross-linked with ferric ions, showing that they have strong antibacterial properties and rapid hemostatic abilities, making them promising candidates for wound dressing applications.
This study found that finite element analysis-guided design improved bubble microneedles' controlled tip separation and insertion strength, supporting effective transdermal and sublingual drug delivery.
26 citations
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June 2020 in “Polymers” This study reported that a magneto-responsive transdermal microneedle system delivered Minoxidil effectively and significantly increased hair density by 800% in mice with androgenetic alopecia after 10 days.
May 2025 in “International Journal of Biological Macromolecules” In this study, an innovative microneedle platform loaded with IGF-1 and modified collagen was reported to significantly promote hair regeneration, enhance neovascularization, and reduce inflammation in a mouse model of androgenetic alopecia, outperforming the commonly used minoxidil treatment.
August 2025 in “Journal of Medical and Biological Engineering” In this study, a needle-free supersonic atomizer delivering Bacopa monnieri extract with hyaluronan was found to enhance hair growth in mice more effectively than the traditional smear method and minoxidil.
2 citations
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January 2018 in “The Korea Journal of Herbology” In this study with C57BL/6 mice, SHJ extract was associated with increased hair growth and density, suggesting potential use in hair care cosmeceuticals, while also enhancing melanin production in melanoma cells.
4 citations
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December 2021 in “Applied sciences” This study observed that a combination of micro-needling and low-level light/laser therapy significantly increased hair density in patients with mild to moderate androgenic alopecia, showing an increase of 12 hairs/cm² after 16 weeks, compared to baseline.
March 2023 in “ACS Applied Materials & Interfaces” This study reports that a water-soluble microneedle patch with minoxidil-loaded microspheres showed similar or better hair regeneration effects in mice with less frequent application compared to daily topical minoxidil.
August 2024 in “International Journal of Pharmaceutics” This study found that a specially designed water-in-oil microemulsion containing Panax notoginseng saponins improved hair density and other hair health indicators in mice with telogen effluvium and androgenetic alopecia, offering a promising multi-mechanism strategy for alopecia treatment with potentially fewer side effects than traditional methods.
4 citations
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May 2014 in “Daehan hanbang so'a'gwa haghoeji/Daehan hanbang soagwa hakoeji” In this study, Ganoderma lucidum extract combined with microneedle therapy promoted hair growth more effectively than microneedle therapy alone in a mouse model of alopecia.
February 2025 in “Research Society and Development” This narrative review compiled evidence suggesting that microneedling can effectively and safely improve skin conditions like scars, hyperpigmentation, and aging, provided it is performed correctly, by stimulating collagen production and enhancing topical treatment penetration.
1 citations
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July 2016 in “PubMed” This study found that 5% minoxidil topical foam used once daily for 24 weeks was well tolerated and significantly improved hair regrowth and scalp coverage in women with female pattern hair loss compared to vehicle foam.
21 citations
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October 2025 in “Advanced Materials” This study found that a newly created biomimetic microneedle platform effectively expedited wound repair in diabetic animal models by reducing inflammation, enhancing angiogenesis, and promoting skin regeneration through targeted drug delivery and immune response modification.
6 citations
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October 2019 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” This study found that rice bran ash extract enhanced melanin biosynthesis-related protein expression in a 3D hair follicle-like tissue model and hair follicle organ culture, suggesting potential for future research in melanogenesis.
January 2021 in “Journal of Entomology and Zoology Studies” This case report describes the effective treatment of psoroptic mange in Large White Yorkshire piglets using ivermectin, cefpodoxime, chlorpheniramine, povidone iodine, and Ascabiol lotion, resulting in full recovery and absence of mites.
7 citations
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March 1990 in “Pigment Cell Research” This animal study observed that while topical MBEH and intraperitoneal phenol induced hair graying in eumelanic mice, they had little effect on pheomelanic mice, and amcinonide reduced certain epidermal melanocytes in both.
April 2022 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study reports that a combination of adult stem cell released molecules and microneedling may be an effective and safe treatment for alopecia, promoting hair regrowth in 12 patients.
4 citations
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February 2015 in “PubMed” This study found that a minoxidil foamable emu oil emulsion significantly promoted hair growth in animals compared to a marketed 5% minoxidil solution, showing increased hair follicles in the anagenic phase.
3 citations
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July 2023 in “Cells” This study found that topical application of recombinant human MG53 protein mitigated nitrogen mustard-induced skin injuries in mice by preserving epidermal integrity and hair follicle structure.