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The Rotterdam Study investigates diseases in older adults and has produced many research findings.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Anorexia and bulimia lead to serious health problems and increased risk of death, requiring aggressive treatment.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Advanced human skin models improve drug development and could replace animal testing.

Low-level laser therapy is safe and can increase hair growth for male and female pattern hair loss.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Early balding men may have insulin resistance, but lifestyle changes can help.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

Human hair follicle dermal cells can effectively replace other cells in engineered skin.

Hair transplants look natural, but the best method is debated, and PRP shows promise for hair regrowth.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Hair follicles are valuable for regenerative medicine and wound healing.