In this study of mouse hair follicles, Raptor was specifically expressed in hair follicle stem cells, while Rictor was mainly found in inner root sheath cells, indicating distinct roles in hair growth stages.
November 2022 in “Journal of Investigative Dermatology” This study generated a transcriptomic map of human hair follicle compartments, providing a database for identifying compartment-specific gene expression which may aid in developing targeted treatments for hair follicle disorders.
April 2018 in “Journal of Investigative Dermatology” This study identified a specific subset of macrophages as a key source of oncostatin M, maintaining hair follicle stem cell quiescence during the resting phase in mice, suggesting a potential target for treating hair disorders.
205 citations
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April 2005 in “Journal of Investigative Dermatology” This study describes a system for generating hair follicles from dissociated cells in mice, suggesting that successful development requires a foundational epithelial platform.
11 citations
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October 2017 in “Journal of Investigative Dermatology” This study found that topical application of mitochondrial electron transport chain inhibitors stimulated hair follicle stem cell activation and hair regrowth in aged mice by promoting lactate production.
8 citations
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September 2011 in “Scanning” This study found that multiphoton microscopy effectively visualizes the microstructure of in vivo mouse skin, offering a clear view of various skin layers and components like corneocytes and collagen fibers.
16 citations
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October 2003 in “Journal of The American Academy of Dermatology” This study describes a 4-year-old boy who exhibits a rare, synchronized pattern of hair growth and shedding, unlike the typical asynchronous pattern seen in humans.
2 citations
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December 2022 in “Journal of Clinical Medicine” This review suggests that, among non-hormonal treatments for menstrual irregularities in adolescents with PCOS, metformin is the most effective and cost-efficient option, particularly in overweight adolescent girls.
35 citations
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May 2019 in “Frontiers in genetics” This study reported that specific non-coding RNAs may regulate the hair follicle cycle in Angora rabbits by acting as competitive endogenous RNAs, enhancing understanding of ncRNA roles in hair growth.
98 citations
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July 2006 in “Neuropsychopharmacology” 2 citations
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October 2024 in “Phenomics” August 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This abstract discusses the non-invasive technique of scalp micropigmentation for hair loss, focusing on its cosmetic effects and customization options, and reports no new research findings.
28 citations
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August 2018 in “BMC genomics” This study found that the DNA methylation status of skin samples from cashmere goats was higher during the telogen stage compared to the anagen stage, identifying genes potentially important for hair follicle development and growth.
27 citations
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December 2006 in “Environmental Science & Technology” This study found that laser ablation-inductively coupled plasma-mass spectrometry can effectively reconstruct time-resolved mercury exposure in micrometer segments of a single hair strand from fish-eaters.
7 citations
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August 2013 in “Facial Plastic Surgery Clinics of North America” This review discusses the indications and technical aspects of megasession hair transplantation and reports no new clinical results.
19 citations
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March 1975 in “British Journal of Dermatology” This study presents a method for extracting and measuring cyclic AMP in small amounts of skin tissue, finding varying levels in the dermis, epidermis, and hair follicles.
10 citations
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January 2016 in “PLOS ONE” This study investigated protein expression changes during mouse hair follicle cycles and suggested their involvement in biological networks, potentially identifying targets for hair disease therapy.
August 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that FGF18 is crucial for regulating hair follicle rest and growth phases, as its absence in mice leads to a shorter resting phase and rapid hair cycling.
1 citations
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December 2007 The micropunctiform technique for hair restoration is safe, simple, and creates a natural hairline.
October 2022 in “Frontiers in Genetics” This study found that miRNAs increase and target mRNAs and lncRNAs decrease from the anagen to telogen phase in mouse hair follicles, and these ceRNA networks may play a role in hair follicle cycling.
15 citations
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October 2012 in “Journal of circadian rhythms” This study found that extracting RNA from equine hair follicles can effectively identify 24-hour oscillations of specific circadian clock genes, offering a valuable non-invasive method to evaluate the equine circadian clock.
149 citations
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July 2017 in “PLoS Biology” This study found that hair follicle patterning in development may arise from a combination of epidermal prepattern signals and mesenchymal self-organisation, with fibroblast growth factor and bone morphogenetic protein activities playing key roles.
29 citations
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June 2005 in “Journal of Zoo and Wildlife Medicine” This study concluded that coat damage in captive rhesus macaques is unlikely caused by parasitic, bacterial, or mycotic infections but may be linked to environmental or behavioral factors affecting hair growth.
June 2023 in “Clinical Case Reports” This report describes a woman with microcystic adnexal carcinoma who underwent successful excisional surgery and hair transplantation, which may be beneficial for treating surgical scars.
February 2026 in “International Journal of Biological Macromolecules” In this study, researchers developed a novel periodate oxidation method for extracting keratin micro-units from waste hair and feathers, achieving yields of 31.28% and 20.64% respectively, enhancing the stability of oil-in-water emulsions and suggesting potential for sustainable biomaterial production.
18 citations
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June 2011 in “Cell stem cell” Two studies in Cell Stem Cell reported that human and mouse somatic cells can be reprogrammed into induced pluripotent stem cells using microRNAs, eliminating the need for ectopic protein expression.
This study found that a high-fat diet in macaques led to severe gastrointestinal inflammation and chronic wasting, with more pronounced effects in females, highlighting the potential risks of certain dietary interventions in obesity models.
51 citations
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November 2005 in “Journal of Medical Primatology” This study observed that hair loss in captive rhesus macaques varies with season, sex, and housing conditions, and is significantly correlated with HPA axis activity as indicated by faecal cortisol metabolites.
January 2022 in “Figshare” Melatonin affects when and how goat hair grows by changing gene activity at different stages.
61 citations
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April 2013 in “PloS one” This study identified numerous genes that change expression across the anagen, catagen, and telogen stages of cashmere goat hair follicle development, highlighting key signaling pathways involved.