25 citations
,
September 2015 in “Clinical Endocrinology” This study found that diagnosing nonclassic congenital adrenal hyperplasia in women based solely on serum 17OHP measurements can lead to false positives, suggesting the need for urinary steroid profiles and genetic testing for confirmation.
11 citations
,
November 2001 in “Journal of Chromatography B: Biomedical Sciences and Applications” This review discusses various chromatographic methods for analyzing finasteride in biological fluids and provides no clinical findings, focusing on detection techniques for different concentration levels.
8 citations
,
November 2020 in “Journal of Cosmetic Dermatology” This preclinical study observed that a nanoencapsulated ingredient complex, AcPi, may prevent hair follicle aging and hair loss by reducing oxidative stress, enhancing mitochondrial activity and WNT/β-catenin signaling, and controlling androgenic metabolism when tested on human scalp cultures.
7 citations
,
July 2022 in “Quality of Life Research” This study found that achieving 80% scalp hair regrowth (SALT score ≤ 20) is considered a meaningful treatment success by expert clinicians-then-patients with ≥ 50% scalp hair loss.
7 citations
,
January 2021 in “Dermatology and therapy” This study confirmed that the Alopecia Areata-Investigator Global Assessment and other clinical outcome assessments are valid and relevant measures of treatment success for alopecia areata patients in Japan, aligning with previous North American findings.
3 citations
,
October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that scalp hair loss is the most bothersome symptom of alopecia areata for both adults and adolescents, highlighting the need for treatments focused on improving scalp hair growth.
2 citations
,
July 2024 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” This study found that alopecia areata presents diverse hair loss patterns and a range of treatment options, though no treatment was universally effective, and significantly impacts patients' psychological well-being.
2 citations
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May 2022 in “The journal of immunology/The Journal of immunology” In vivo using the C3H mouse model, this study observed that BST2 expression occurs before hair loss in alopecia areata and is followed by an increase in epidermal γδ T cell numbers.
1 citations
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June 2025 in “Environmental Research” In this study, researchers reported that adult females approaching menopause in Canada generally had similar or lower blood concentrations of toxic, essential, and trace elements compared to their peers, but most participants showed zinc levels below the proposed adequacy threshold.
1 citations
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November 2022 in “Journal of the Endocrine Society” This study found that US adults with classic congenital adrenal hyperplasia most preferred a hypothetical adjunctive therapy that prevents glucocorticoid-induced weight gain over other potential benefits.
April 2026 in “Research Square”
December 2025 in “Brazilian Journal of Hair Health” This integrative review developed a Spiral Model to better represent human hair follicle dynamics and aging, which may assist in distinguishing natural aging from pathological changes and improving trichological interventions.
September 2025 in “Ensaios USF” This study developed a solid shampoo formulation with conditioning properties, highlighting its feasibility and environmental benefits compared to conventional shampoos due to biodegradable packaging and no water in its composition, thus offering a sustainable alternative in the cosmetic industry.
June 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that in alopecia areata, epidermal γδ T cells and macrophages contribute to the disease alongside CD8 T cells, with the expression of BST2 marking interferon-driven immune activation in both mouse and human skin, which decreases following treatment with the JAK inhibitor tofacitinib.
January 2025 in “Ciência Rural” This case study reports a cutaneous adverse drug reaction in a dog caused by prolonged topical exposure to benzyl benzoate, leading to irritant contact dermatitis, but healing occurred within three weeks after changing treatment.
December 2024 in “Skin Appendage Disorders” This case report highlights the diagnostic challenges of distinguishing folliculotropic mycosis fungoides from alopecia areata and lichen planopilaris, emphasizing the importance of histopathological evaluation for accurate diagnosis and treatment.
April 2021 in “Research Square (Research Square)” This study concluded that achieving 80% or more scalp hair, corresponding to a SALT score of ≤20, represents a clinically meaningful treatment success for patients with alopecia areata experiencing ≥50% hair loss.
60 citations
,
September 2010 in “Journal of the American Academy of Dermatology” Small white dots on the scalp seen with a dermoscope correspond to sweat ducts and vary with different hair disorders.
52 citations
,
January 2023 in “Annual Review of Immunology” This review discusses how immune mechanisms contribute to the regeneration and repair of epithelial tissues and highlights their potential role in both disease and therapeutic innovation; it reports no new clinical results.
42 citations
,
March 2015 in “Anais Brasileiros de Dermatologia” This study reports two cases of alopecia associated with anti-TNF therapy, highlighting a new entity combining features of alopecia areata and psoriatic alopecia.
33 citations
,
September 2012 in “Australasian Journal of Dermatology” This article reviews trichoscopic signs of chemotherapy-induced alopecia, including exclamation marks, but reports no new clinical results.
30 citations
,
June 2017 in “Talanta” This review discusses the critical parameters for MALDI IMS sample preparation in skin analysis and highlights its applications in wound healing, neoplasia, and infection research, but reports no new clinical results.
24 citations
,
November 2008 in “Arquivos Brasileiros de Endocrinologia & Metabologia” In this study, mutations in the vitamin D receptor were identified in Brazilian children with rickets and alopecia, leading to impaired receptor activation and reduced 24-hydroxylase expression.
21 citations
,
May 2016 in “Progress in Neuro-Psychopharmacology and Biological Psychiatry” Diazepam's effects on anxiety and memory differ between male and female rats due to hormonal influences.
20 citations
,
April 2011 in “British Journal of Dermatology” Reflectance confocal microscopy can tell apart white dots on the scalp as either sweat gland ducts or hair follicle openings.
18 citations
,
January 2021 in “Skin Research and Technology” This study found that high-frequency ultrasound was effective in localizing deep tumor margins in basal cell carcinoma, suggesting its utility in selecting therapeutic approaches.
14 citations
,
June 2013 in “Anais Brasileiros de Dermatologia” This report found follicular red dots in patients with scalp pigmentary disorders, suggesting they might be linked to the scalp's vascular structure and may have implications for conditions like discoid lupus erythematosus.
14 citations
,
January 2012 in “International Journal of Dermatology” This case report describes oleoma on the thighs and buttocks appearing two years after an injection for cellulite treatment, suggesting the need for more research to ensure the procedure's safety and efficacy.
5 citations
,
August 2020 in “Stem Cell Research & Therapy” This study found that combining adipose-derived mesenchymal stromal cells with meglumine antimoniate reduced lesion size and parasite load in mice with leishmaniasis, suggesting potential for improved treatment.
5 citations
,
October 2016 in “Anais Brasileiros de Dermatologia” This report describes a rare case of leprosy involving the scalp, a location not typically conducive to Mycobacterium leprae infection, and adds to existing literature without presenting new experimental findings.