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research Activation of Fibroblast and Papilla Cells by Glycolipid Biosurfactants, Mannosylerythritol Lipids.
In this study, mannosylerythritol lipids from soybean oil notably increased fibroblast and papilla cell viability, suggesting potential as a hair growth agent.
research Photo-Responsive Ascorbic Acid-Modified Ag2S–ZnS Heteronanostructure Dropping pH to Trigger Synergistic Antibacterial and Bohr Effects for Accelerating Infected Wound Healing
This study found that PEGylated Ag₂S-ZnS@TGA-AA heteronanostructures, activated by light exposure, showed synergistic antibacterial effects against multidrug-resistant bacteria, significantly accelerating the healing of MRSA-infected wounds in comparison to untreated wounds.
research Roles of two sphingomyelin synthase isoforms in murine hair
This study found that knockout mice lacking SMS1 showed reduced body weight and hair loss, indicating a role for SMS1 in normal growth and hair health.
research Isolation and characterization of a sheep cysteine-rich cuticle keratin pseudogene
This study found that a cuticle keratin gene in sheep is a pseudogene due to gene duplication and mutations, lacking expression in vivo.
research Anti-inflammatory effects on murine macrophages of ethanol extracts of Lygodium japonicum spores via inhibition of NF-κB and p38
This study observed that ethanol extracts of Lygodium japonicum spores significantly reduced inflammatory responses in LPS-stimulated murine macrophages in vitro by negatively regulating p38 MAPK and NF-κB.
research Partial Purification and Characterization of Two Distinct Types of Caspases from Human Epidermis
This study isolated and characterized two distinct types of caspase-like proteases from human epidermis, suggesting their involvement in keratinocyte differentiation and apoptosis processes.
research In-silico analysis of papain fibrinolytic mechanism from Carica papaya
This study used in-silico analyses to investigate papain's potential as a fibrinolytic agent and found that certain fibrin peptides displayed strong interactions with papain, suggesting it may be beneficial for cardiovascular disease treatment.
research Decision letter: Structural basis of malodour precursor transport in the human axilla
This study reports that a specific transporter protein in Staphylococcus hominis is responsible for transporting a malodour precursor, thereby playing a key role in human body odor production.
research Lamins in development, tissue maintenance and stress
This review discusses the role of lamins in development, tissue maintenance, and stress response, and does not report new experimental findings.
research SOX9 as a key regulator of tissue remodelling and epithelial cell fate transitions.
In this review, the authors discuss how SOX9 functions as a key regulator of epithelial cell fate and tissue repair, suggesting its role in integrating environmental signals, which could inform regenerative medicine approaches despite potential risks like fibrosis and cancer.
research Werewolf, there wolf: variants in Hairless associated with hypotrichia and roaning in the lykoi cat breed
In this study, researchers identified loss of function variants in the HR gene as likely causes of the distinct roaning hair coat seen in lykoi cats.
research Nano-Transfersomes of Vitamin-E and Aloe-Vera for The Management of Psoriasis
This research found that Nano-Transfersomes containing Vitamin E and aloe vera showed improved permeability and prolonged drug release compared to a marketed formulation, with no skin irritancy observed in mice, potentially offering a sustainable and biocompatible option for psoriasis management.
research Enzyme Typing of Human Hair Roots
This study explored the potential of using isoenzyme detection after electrophoresis to characterize human hair, though no new clinical results are reported.
research Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria
This study found that enzyme replacement therapy in mice with a severe form of classical homocystinuria improved metabolic patterns and alleviated many clinical symptoms.
research White Lupin Cluster Root Acclimation to Phosphorus Deficiency and Root Hair Development Involve Unique Glycerophosphodiester Phosphodiesterases
This study suggests that the GPX-PDE1 and GPX-PDE2 genes in white lupin enhance root hair development and contribute to Pi limitation acclimation by facilitating glycerophosphodiester degradation.
research An Electron Microscopy Study of Keratin Degradation by the Fungus Microsporum gypseum in vitro
This study found that the fungus Microsporum gypseum enzymatically degrades keratin in human hair, with the sequence of degradation reflecting the keratinization and cystine content of individual hair components in vitro.
research Increased expression of psoriasin (S100A7) and interleukin 17 (IL-17) in lesional skin in lichen planopilaris
This study suggests a potential role for S100A7 and IL-17 in the pathogenesis of lichen planopilaris.
research SYNTHESIS OF INOSITOL IN MICE
This study found that mice can synthesize inositol, but this ability is impaired when pantothenic acid is lacking in their diet.
research Pathogenicity and enzyme screening of some selected non-dermatophytic moulds
This study found that certain non-dermatophytic moulds, specifically *Absidia* sp., *Cladosporium tenuissimum*, and *Aspergillus welwitschiae*, can cause skin symptoms such as discoloration and lesions in albino mice, suggesting potential virulence due to enzyme activity.
research A patient with eosinophilia-myalgia syndrome.
This case report describes a patient with eosinophilia-myalgia syndrome related to L-tryptophan use, detailing the specific symptoms and laboratory abnormalities observed.
research HAIR GROWTH PROMOTING ACTIVITY OF LANGIR BARK (Albizia saponaria LOUR.) ETHANOL EXTRACT: In-vivoASSAY
This study found that ethanol and water extracts of Albizia saponaria bark significantly stimulated hair growth in male rabbits over 24 days.
research LIPOSOMES
This article reviews the role of liposomes in dermatology and does not report new clinical results.
research 1434 Epithelially derived MPZL3 negatively regulates murine and human sebaceous gland size and sebocyte proliferation
This study found that MPZL3 plays a crucial role in controlling sebaceous gland size and sebocyte proliferation in mice and humans, implicating its potential involvement in skin disorders like acne and psoriasis.
research Ishige sinicola extract stimulates osteoblast proliferation and differentiation via the bone morphogenetic protein 2/runt-related gene 2 signalling pathway
This study found that Ishige sinicola extract stimulated osteoblast differentiation and bone formation in MC3T3-E1 cells, suggesting potential use for osteoporosis prevention and treatment.
research In Silico Characterization and Analysis of Clinically Significant Variants of Lipase-H (LIPH Gene) Protein Associated with Hypotrichosis
In this in silico study, researchers analyzed nonsynonymous SNPs in the LIPH gene linked to hypotrichosis and identified three potentially harmful variants (W108R, C246S, and H248N) out of 215 total, using sequence- and architecture-based bioinformatics techniques to differentiate between harmful and benign SNPs.
research ELECTRON MICROSCOPE STUDIES OF HAIR AND WOOL
This article reports electron microscope studies on the structure of hair and wool, but it does not present new clinical findings.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
This review discusses the discovery and potential therapeutic uses of proteasome inhibitors across various diseases, including cancer and autoimmune conditions, but does not present new clinical data.
research Author response: Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing
This study found that the Piezo1 ion channel reduces the efficiency of keratinocyte migration, and its inhibition in mice accelerates wound healing.
research Arachidonate 12-Lipoxygenase Inhibitors Promote S100A3 Citrullination in Cultured SW480 Cells and Isolated Hair Follicles
This study found that inhibiting arachidonate 12-lipoxygenase (ALOX12) may enhance hair cuticle maturation by increasing S100A3 protein citrullination and promoting cuticular differentiation in isolated human hair follicles.