Pathogenicity and Enzyme Screening of Some Selected Non-Dermatophytic Molds

    June 2024 in “ Access Microbiology ”
    CN Nwofor, NE Onyenwe, CB Osuoha
    TLDR Some moulds can cause skin issues and produce enzymes that may increase their harmfulness.
    The study investigated the pathogenicity and enzyme activity of 10 non-dermatophytic moulds isolated from cattle skin using albino mice. It found that *Absidia* sp., *Cladosporium tenuissimum*, and *Aspergillus welwitschiae* caused skin discoloration, lesions, and alopecia, indicating their potential to cause cutaneous mycoses. Enzyme screening showed significant activity for keratinase, amylase, protease, lipase, and cellulase, particularly in *Pestalotiopsis microspora* and *Aspergillus welwitschiae*. The study suggests that the virulence of these moulds may be linked to their ability to secrete hydrolytic enzymes.
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