Pathogenicity and Enzyme Screening of Some Selected Non-Dermatophytic Molds

The study examined the pathogenicity and enzyme activity of ten non-dermatophytic moulds isolated from cattle skin, using albino mice for testing. It found that Absidia sp., Cladosporium tenuissimum, and Aspergillus welwitschiae caused discoloration, lesions, and alopecia on mice skin, indicating potential virulence. Enzyme screening revealed significant activity for enzymes such as keratinase and amylase, particularly in Pestalotiopsis microspora and Aspergillus welwitschiae. These findings suggest that non-dermatophytic moulds, traditionally seen as colonizers, may contribute to cutaneous mycoses due to their enzyme secretion capabilities. The study underscores the importance of antifungal therapy and suggests alternative remedies, like medicinal plants, to combat infections.