Activation of Fibroblast and Papilla Cells by Glycolipid Biosurfactants, Mannosylerythritol Lipids

    January 2010 in “ Journal of oleo science ”
    Tomotake Morita, Masaru Kitagawa, Shuhei Yamamoto, Michiko Suzuki, Atsushi Sogabe, Tomohiro Imura, Tokuma Fukuoka, Daï Kitamoto
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    TLDR MEL-A from soybean oil can boost fibroblast and papilla cells, potentially aiding hair growth.
    Mannosylerythritol lipids (MELs), particularly the di-acetylated MEL (MEL-A) produced from soybean oil, significantly increased the viability of fibroblast cells by over 150% and dramatically activated papilla cells at 0.001 microg/L, suggesting its potential as a new hair growth agent. Conversely, MEL-A from olive oil and mono-acetylated MEL (MEL-B) showed little to no cell activation. The study highlighted the promising application of MEL-A from soybean oil in cosmetics, especially for stimulating hair growth.
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