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Accurate diagnosis of SLE requires extensive testing due to its complex symptoms.

RDW can be a useful marker for inflammation in alopecia areata patients.

The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.

Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.

Antimalarial agents are effective for LPP, and intralesional steroids are effective for FFA.

Fat under the skin can help hair grow longer, darker, and increase cell growth.

Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.

The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.

Different types of stem cells in the skin contribute to the variety of melanoma forms.

A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.

Low-level laser therapy helps hair growth and reduces hair loss with few side effects.

Hair pattern in androgenetic alopecia overlaps with scalp and bone demarcations, with distinct gene profiles affecting susceptibility.

Atopic dermatitis may have genetic causes and can be treated with pharmacologic methods, glycerin creams, and controlling Staphylococcus aureus colonization.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.