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TLR4 is important in aging-related diseases and could be a new treatment target.

Gendered social factors, not just biology, contribute to sex differences in adverse drug events.

Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Immune cells are essential for early hair and skin development and healing.

Chicken feather growth involves specific genes and shares similarities with hair development.

Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

The document encourages attending the 2023 Dermatology Nurses' Association Convention.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

4-octyl itaconate may prevent hearing loss caused by the drug cisplatin by activating certain cell protection pathways.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Eyelash alopecia areata often goes undiagnosed and can lead to complete eyelash regrowth, especially in younger patients.

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

Baldness, especially at the front, may lower the risk of testicular cancer by 31%, but its link to prostate cancer is unclear.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Lenvatinib and sorafenib are generally safe but need dose adjustments due to side effects.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Patients who survive critical illness often face long-lasting physical, mental, and cognitive issues, with many unable to return to work within a year.

Nonobese, normotensive Indian women with PCOS may have a higher risk of heart problems linked to inflammation and insulin resistance.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.