February 2018 in “The American Journal of Gastroenterology” This study observed that intravenous ferric carboxymaltose did not inhibit the drug-induced reduction of inflammatory activity in patients with inflammatory bowel disease, as indicated by lower CRP levels.
13 citations
,
February 2018 in “Dermatologic Therapy” This study found that 65.2% of female pattern hair loss patients showed significant hair growth improvement with a daily dosage of 2.5 mg finasteride, with better outcomes in patients with lower initial Ludwig scores and older age at onset.
February 2022 in “Pakistan Journal of Medical and Health Sciences” This study reported that finasteride administered at 2.5 mg/day was clinically effective in 62% of women with female pattern hair loss, with greater efficacy observed in those who were premenopausal or had a lower Ludwig score.
This study found that the novel alcohol-free topical foam CG2001, combining minoxidil and finasteride, was safe and well-tolerated in Chinese males with androgenetic alopecia, with significantly lower systemic exposure to finasteride compared to oral administration, potentially reducing sexual side effects.
4 citations
,
May 2025 in “Open Access Journal of Contraception” This study suggests that lower-dose ethinyl estradiol formulations and progestin-only contraceptives may offer safer options for managing PCOS in obese women due to minimal metabolic effects.
11 citations
,
April 2018 in “The Journal of urology/The journal of urology” This study found that post-void residual volume was not linked to worsening urinary symptoms or increased risk of recurrent urinary tract infections in patients with multiple sclerosis.
1 citations
,
August 2021 in “Cosmoderma” This study reviewed literature on low-dose oral minoxidil as a treatment for hair loss, finding good compliance and tolerability, with mild adverse effects like hypertrichosis, which increase with higher doses.
This literature review explores the mechanism of action, pharmacokinetics, safety, and efficacy of low-dose oral minoxidil as a treatment for various non-androgenic types of alopecia, finding it to be a promising alternative for these conditions despite the need to establish optimal dosing for different demographics.
1 citations
,
December 2019 in “World rabbit science” This study found that high concentrations of supplemental cobalt inhibited hair follicle development in rabbits, potentially involving the mTOR-BMP signaling pathway.
July 2024 in “Skin Appendage Disorders” In this study, researchers found that low-dose oral minoxidil for androgenetic alopecia in men generally showed a good safety profile, with hypertrichosis being the most frequent side effect, while systemic side effects like dizziness and hypotension were less common and no life-threatening effects were observed.
November 2024 in “Skin Appendage Disorders” In this study of patients with androgenetic alopecia taking off-label low-dose oral minoxidil, adverse events like dizziness/lightheadedness, hypertrichosis, and extremity edema were observed in 14.9% of patients, with females experiencing more adverse events; higher doses increased dizziness risk, leading researchers to recommend cautious dosing approaches.
May 2024 in “IntechOpen eBooks” In this study, the authors explored the efficacy of hyperbaric oxygen therapy for typical sports injuries and cosmetic surgical wounds, finding that a hormetic dose-response relationship could explain the observed successes, contrary to prevailing expert opinion that deemed this treatment ineffective for normal wounds.
February 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Low-dose oral minoxidil is a promising, safe treatment for various hair diseases, improving hair thickness and density, but more research is needed on long-term side effects and treatment duration.
74 citations
,
January 2006 in “Endocrine journal” Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.
24 citations
,
September 2002 in “Dermatologic Surgery” This study suggests that transplanting hair to new nonscalp sites affects their growth and survival rates, though the hair diameter remains consistent.
15 citations
,
December 2019 in “European Journal of Dermatology” This study identified new and recurrent missense mutations in the PHGDH and PSAT1 genes, implicating them in the pathogenesis of Neu-Laxova syndrome in Chinese patients.
September 2002 in “Dermatologic Surgery” This study suggests that hair transplantation to new nonscalp sites affects the growth and survival rates of transplanted hairs, while the diameter remains unchanged.
6 citations
,
January 2021 in “Journal of The American Academy of Dermatology” This letter discusses adverse events related to low-dose oral minoxidil for alopecia, highlighting age-related risks and stressing the importance of contraindication awareness with no new clinical results presented.
28 citations
,
July 2017 in “Journal of Endocrinological Investigation” This study suggests that early onset androgenetic alopecia in men may indicate a male PCOS equivalent, possibly leading to higher risks of metabolic and cardiovascular disorders later in life.
4 citations
,
May 2017 in “Hair transplant forum international” This article discusses the historical development and recent rejuvenation of implanter pens in hair restoration surgery and does not present new research findings.
August 2023 in “Research Square (Research Square)” This study found that among patients with inflammatory bowel disease, those with the NUDT15 mutation had a reduced tolerance for thiopurine dosage over the long term and were more likely to require hospitalization and surgery compared to those without the mutation.
13 citations
,
December 2021 in “Toxics” In this study, PEGDE above 10,000 μg/mouse caused subcutaneous toxicity including ulceration in mice, but did not affect liver, spleen, or kidney tissues.
1 citations
,
May 2008 in “Toxicon” This study found that BOTOX doses of 75–100 U effectively reduce postvoiding residual urine and detrusor pressure in patients with detrusor sphincter dyssynergia.
53 citations
,
January 1985 in “Acta obstetricia et gynecologica Scandinavica” This study found that an 8-month treatment with a low-dose oral contraceptive significantly reduced testosterone levels and hair growth in women with polycystic ovary syndrome and hirsutism, with minimal side effects.
January 2024 in “Dermatology practical & conceptual” In this study, researchers found that the peripilar sign in patients with androgenetic alopecia does not indicate perifollicular infiltrate but is more frequent in individuals with lighter skin types due to contrast with the skin.
21 citations
,
March 2021 This study reviewed the literature on low-dose oral minoxidil as a primary treatment for various hair loss disorders, concluding that it is a successful and well-tolerated alternative to topical minoxidil for patients with poor adherence to other therapies.
May 2025 in “International Journal of Trichology” This prospective study reported that 5 mg daily oral low-dose minoxidil over 24 weeks led to a high prevalence of hypertrichosis in 93% of male androgenetic alopecia patients, particularly affecting younger individuals, but generally had minimal impact on patients’ quality of life.
15 citations
,
April 2022 in “Immunology” This review discusses sex differences in immune responses to COVID-19 and highlights that males tend to experience more severe symptoms and higher mortality but reports no new clinical findings.
1 citations
,
July 2017 in “The Journal of Urology” In this study, low dose finasteride or dutasteride treatment was found to reduce prostate specific antigen levels in men with androgenetic alopecia, though levels sometimes remained stable or increased in those with low baseline PSA.
July 2023 in “Journal of Clinical Medicine” In this study, researchers investigated factors predicting resistance to clomiphene citrate in women with anovulatory PCOS, identifying AMH and SHBG levels as significant indicators, but they found no reliable thresholds for predicting resistance to the standard 50 mg/day dose.