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In this study, researchers identified a novel homozygous variant in the FAM83G gene responsible for autosomal recessively inherited palmoplantar keratoderma with curly hair in a consanguineous Pakistani family, suggesting FAM83G plays a crucial role in skin and hair homeostasis.

This review summarizes structural insights into androgen receptor dynamics, highlighting its flexibility in binding numerous partners, which may explain adaptive resistance mutations in cancer and loss of function in androgen insensitivity syndrome.

This chapter reviews therapies for skin and corneal regeneration and hair loss, discussing various treatments but presenting no new research findings.

This review discusses the role of tumor suppressors in controlling tumor-associated inflammation and suggests that targeting this inflammation may counteract the effects of tumor suppressor loss.

2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.

This review found a significant immunological link between diffuse alopecia areata and autoimmune thyroid disorders, particularly Hashimoto's thyroiditis, highlighting the importance of early recognition and thyroid function evaluation to improve clinical management and avoid diagnostic delays.

This source reviews advancements in microneedle-based cosmeceutical delivery, discussing new technologies and highlighting a burgeoning area of research involving microneedling combined with stem cell delivery for anti-aging, without finding measurable changes in skin barrier function or appearance during the study period.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

This study found that cortisone reductase deficiency is caused by inactivating mutations in the H6PD gene, affecting cortisol metabolism by preventing 11β-HSD1 enzyme function.

This study found that collagen VI influences hair follicle growth and wound-induced regrowth by activating the Wnt/β-catenin signaling pathway in mice, suggesting potential therapeutic targets for hair loss.

In this study, only European-ancestry females showed a linear increase in cutaneous malignant melanoma risk with age, potentially due to the loss of HPV-infected androgenic follicles after menopause.

This study found that phenoxyethanol is the most common contact allergen in over-the-counter hair loss products, but its role in the development or exacerbation of frontal fibrosing alopecia remains unclear.

Ceramide Synthase 4 is crucial for healthy skin barrier function.

This study identified a gene variant in the TRPV3 gene that may explain the suri alpaca phenotype, characterized by longer and less crimped fleece, suggesting this variant's involvement in the development of these hair characteristics compared to the huacaya phenotype.

This review discusses the functions of SARS-CoV-2 non-structural proteins in facilitating immune evasion and highlights possible therapeutic strategies, reporting no new clinical results.

A mutation in the KRT25 gene causes woolly hair and hair loss.

This article reviews the genetic basis, diagnostic approaches, and treatment options for nude severe combined immunodeficiency, but does not present any new research findings.

In this study, genetic variants in the KRT25 and SP6 genes were found to be responsible for curly hair in horses, with the KRT25 variant also causing hypotrichosis due to an epistatic effect.

This review discusses the potential role of a PADI3 gene variant in central centrifugal cicatricial alopecia among African-American women but reports no new clinical results.

This study found that the ablation of Esrp1 and Esrp2 disrupts epithelial tight junctions by affecting Arhgef11 isoform expressions, highlighting a potential mechanistic link between splicing alterations and epithelial barrier defects.

In this study, researchers characterized the retinal structure and function of the Oat^rhg mouse model of gyrate atrophy, finding localized atrophy without significant retina-wide functional impact, suggesting the model may be useful for testing new treatments using multimodal retinal imaging.

This study revealed that in androgenic alopecia, the proximal attachment of the arrector pili muscle to the hair follicle is often lost or significantly reduced.

This case report describes a 42-year-old Indian female with acute diffuse and total alopecia who experienced sudden diffuse hair loss within one day, differentiating it from telogen effluvium through specific dermoscopic findings.

A specific gene mutation causes severe skin and nail issues and hair loss.

This study investigates the potential causal relationship between hypothyroidism and hair loss conditions like alopecia areata and androgenetic alopecia, noting that previous studies have reported inconsistent findings. Results are not yet detailed.

This historical review examines the diagnostic and etiological understanding of alopecia areata, emphasizing the evolution of theories and the impact of immunological data, while providing no new clinical results.

This review discusses the etiology, pathogenesis, clinical presentation, and treatment of frontal fibrosing alopecia, noting the lack of clinical trial data and limited observational treatment results.

This study identified significant genetic associations with frontal fibrosing alopecia at four genomic loci, suggesting it is a genetically predisposed immuno-inflammatory disorder influenced by the HLA-B*07: 02 allele.

This study identified mutations in the STUB1 gene linked to hereditary cerebellar ataxia with cognitive impairment, revealing potential effects on protein function and patient symptoms, including accelerated aging.

This review discusses the role of the immune niche in hair follicle regeneration and its impact on different forms of alopecia, highlighting research gaps and potential therapeutic strategies.