May 2026 in “Frontiers in Oncology” In this study, alopecia areata was associated with a statistically significant reduction in melanoma incidence, but not in overall skin cancer risk, highlighting the need for cautious interpretation due to heterogeneity.
52 citations
,
January 2001 in “Eye” This review discusses challenges in treating CMO associated with uveitis and highlights the need for prospective studies to guide therapy, as current treatments are largely empirical and potentially harmful.
26 citations
,
February 2022 in “Annals of Palliative Medicine” This study found that ultra-pulse CO2 fractional laser treatment improved skin smoothness and total skin lesion scores more effectively in patients with depressed acne scars compared to other treatments.
15 citations
,
November 2024 in “EClinicalMedicine” This abstract does not report specific study results but describes the funding and collaboration involved in developing the International PCOS Guidelines by multiple health research organizations.
15 citations
,
April 2020 in “Journal of The American Academy of Dermatology” This article notes the lack of physician-reported outcome studies supporting the efficacy of off-label spironolactone in treating female pattern hair loss, despite its common prescription alongside FDA-approved topical minoxidil.
14 citations
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March 2014 in “Journal of The American Academy of Dermatology” In this study, symmetrical acrokeratoderma was observed to frequently occur alongside ichthyosis vulgaris, with no specific therapy available for the condition.
9 citations
,
February 2011 in “Biologics: Targets & Therapy” This review discusses topical calcineurin inhibitors for cutaneous lupus erythematosus and reports no new clinical findings; the authors emphasize the need for more comparative studies with corticosteroids.
3 citations
,
January 2015 in “Evidence-based Complementary and Alternative Medicine” This review discusses pumpkin seed oil as a potential treatment for androgenetic alopecia but reports no clinical results on its effects on frontal hair loss; it emphasizes the need for further research.
2 citations
,
January 2022 in “Dermatologic Therapy” Natural products like saw palmetto, caffeine, melatonin, marine extracts, rosemary oil, procyanidin, pumpkin seed oil, and cannabidiol oil could potentially treat male hair loss.
1 citations
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July 2020 in “Journal of The American Academy of Dermatology” This review discusses the potential mechanisms by which intradermal botulinum toxin may affect androgenetic alopecia but notes that high-evidence clinical trials have yet to show conclusive results.
November 2025 in “Journal of the European Academy of Dermatology and Venereology” This study found that JAK inhibitor treatment in patients with alopecia areata was associated with a lower incidence of major depressive disorder and decreased antidepressant usage.
September 2025 in “Acta Dermato Venereologica” Intralesional corticosteroids may be more effective than cryotherapy for hair regrowth in alopecia areata.
June 2025 in “Frontiers in Pharmacology” This systematic review and meta-analysis found that oral minoxidil improved hair loss symptoms in many patients, with significant improvement in 35%, but 27% experienced adverse events, highlighting the need for further research to confirm its safety and efficacy.
In this narrative review, the authors concluded that while high-quality evidence for systemic therapies in pediatric alopecia areata is scarce, Janus kinase inhibitors have the most systematic support, with oral minoxidil and dupilumab also reported as potentially beneficial in certain cases.
February 2025 in “Skin Appendage Disorders” This scoping review found that most of the 64 alopecia areata patients treated with upadacitinib in existing reports experienced significant hair regrowth, with mild side effects, but the authors call for larger studies to confirm these outcomes.
This correspondence suggests that while patients with Raynaud phenomenon may develop connective tissue disorders, physicians should consider this possibility without assuming for certain that progression will occur.
October 2020 in “Journal of Pakistan Association of Dermatology” This analysis of seven studies explored the impact of finasteride (1mg/day for androgenic alopecia) on sperm concentration, finding that in most studies, sperm concentration increased after stopping treatment, but the largest study showed no change during or after treatment.
73 citations
,
April 1999 in “Dermatologic Clinics” This article reviews patient selection and treatment protocols for various light-based hair removal systems but presents no new clinical results.
26 citations
,
August 2008 in “Clinical endocrinology” This paper summarizes proceedings from a PCOS Special Interest Group, reporting recent advances in the understanding of PCOS follicular abnormalities, associated cardiovascular risks, and dermatological issues, but does not present new clinical findings.
23 citations
,
November 2007 in “Journal of cosmetic dermatology” This study concluded that both phosphatidylcholine alone and with organic silicium effectively reduced submental fat, achieving optimal results after three sessions with mild and temporary adverse effects.
11 citations
,
September 2006 in “European Urology Supplements” Combination therapy for BPH is cost-effective, especially for men with larger prostates.
4 citations
,
June 2025 in “Current Urology Reports” This study found that while new treatments like Optilume, Rezum, and Aquablation have minimal risks of sexual dysfunction, they offer less improvement in lower urinary tract symptoms compared to traditional surgeries like TURP, though Aquablation does reduce ejaculatory dysfunction more effectively than TURP.
2 citations
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November 2025 in “Biomedicines” This review explores how platelet- and marrow-derived biologics like PRP and BMAC exhibit both regenerative and antimicrobial properties useful in musculoskeletal conditions and wound healing, though their clinical outcomes are affected by preparation inconsistencies and lack of standardized protocols.
2 citations
,
April 2017 in “Plastic and Aesthetic Nursing” This discussion reviews the trend towards nonsurgical hair loss treatments, emphasizing that options like platelet-rich plasma therapy are increasingly used despite not being covered by Canadian health insurance; it presents no clinical findings.
1 citations
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June 2025 in “Preprints.org” This research review found that climate change exacerbates skin conditions like photoaging, inflammatory dermatoses, and skin cancers by causing oxidative stress and inflammation, suggesting that dermatological practices should incorporate environmental and multicultural considerations to optimize patient outcomes in diverse populations.
1 citations
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January 2024 in “Advances in Orthopedics” This review concludes that platelet-rich plasma injections significantly improve knee joint function in managing knee osteoarthritis compared to other treatments.
1 citations
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June 2023 in “Journal of Patchouli and Essential Oil Products” This literature review suggests that patchouli essential oil may help reduce eczema symptoms in infants and young children due to its anti-inflammatory, antimicrobial, and antioxidant properties, though it highlights the need for further standardized studies to confirm optimal use and safety.
June 2026 in “British Journal of Dermatology” This study evaluated the real-world use of ritlecitinib for severe alopecia areata in the UK, reporting that 37% of patients achieved significant hair regrowth by week 36, with no serious adverse effects noted, although response varied with disease duration.
April 2026 in “SHILAP Revista de lepidopterología” This study reviews the therapeutic applications and evidence around punch-based dermatologic techniques, highlighting their varying effectiveness and precision across different conditions, but emphasizes the need for further standardized research.
April 2026 in “Expert Opinion on Biological Therapy” This review discusses prurigo nodularis and reports no new results, emphasizing the need for further research into its pathophysiology and treatment options.