Reply to: The Effect of Intradermal Botulinum Toxin on Androgenetic Alopecia and Its Possible Mechanism

This document is a reply to a letter discussing the use of botulinum toxin in treating androgenetic alopecia (AGA). The authors of the reply discuss their own systematic review of the existing data on the use of botulinum toxin in alopecia, which found that the main mechanism of action reported by authors in AGA was a relaxation of the muscles of the scalp, allowing for better oxygenation of tissues and increased vascular flow. The authors also discuss the need for higher doses of botulinum toxin to obtain efficacy and the importance of long-term studies to determine the lasting effects of treatment. Overall, the authors congratulate the original authors on their new axis of research and hope it will lead to robust conclusions on the use of botulinum toxin in AGA.