29 citations
,
March 2000 in “Journal of Investigative Dermatology” The gene for Marie Unna hereditary hypotrichosis is located on chromosome 8p21.
21 citations
,
November 2017 in “Cochrane library” This study concluded that laparoscopic ovarian drilling does not clearly improve menstrual regularity or androgenic symptoms in PCOS compared to most medical treatments, but it may have fewer gastrointestinal side effects than metformin plus clomiphene.
14 citations
,
May 2020 in “Drug Testing and Analysis” This study reports that hair analysis could potentially monitor metformin use in diabetic patients, suggesting a possible correlation between daily dose and concentration in dark hair but not in light hair.
6 citations
,
September 2014 in “Food Additives & Contaminants: Part A” This study developed a new method for detecting 30 hormones in anti-aging functional foods, demonstrating good sensitivity and reliability, and identified seven hormones in four out of 14 samples tested.
6 citations
,
May 2010 in “The Journal of Dermatology” A woman with anorexia developed gout from self-induced vomiting.
4 citations
,
January 2018 in “Forensic Science International” This study reported that a newly developed UHPLC-MS/MS method detected illegal synthetic hair-growth compounds in 10% of 76 hair-growth products, highlighting the need for ongoing monitoring to protect public health.
4 citations
,
September 2010 in “Journal of Dermatological Science” This article reviews keratosis follicularis squamosa, a keratinizing disorder predominantly found in the Japanese population, but reports no new clinical results.
4 citations
,
March 2000 in “Journal of Investigative Dermatology” The gene for Marie Unna hereditary hypotrichosis is located on chromosome 8p21, near the hairless gene.
3 citations
,
December 2011 in “Journal of Gynecologic Surgery” In this study, laparoscopic ovarian diathermy with three to five punctures per ovary improved reproductive outcomes for women with clomiphene-resistant polycystic ovary syndrome, while more than six punctures may cause excessive ovarian damage.
2 citations
,
January 2016 in “Scientifica” Researchers created a reliable method to measure dexpanthenol and resorcinol in hair products.
2 citations
,
March 2011 in “Infertility” This review highlights that while lifestyle changes may help with many ovulatory disorders, oocyte donation is considered a viable option for patients who cannot undergo ovulation induction; it reports no new results.
This review found that surgical treatments such as laparoscopic ovarian drilling and transvaginal hydrolaparoscopy may help induce ovulation in over 50% of PCOS patients who are resistant to drug therapy, with more than 40% achieving pregnancy, though miscarriage and ectopic pregnancy rates were noted.
April 2020 in “Indian Journal of Forensic Medicine & Toxicology” This study found that laparoscopic ovarian drilling significantly improved hormone levels and menstrual irregularity, leading to increased ovulation and a pregnancy rate of 26% among women with PCOS-related infertility.
June 2019 in “The Medical journal of Basrah University” This study found that laparoscopic ovarian drilling effectively decreased LH and testosterone levels, aiding fertility in PCOS patients nonresponsive to certain medications, without negatively impacting ovarian reserve.
May 2015 in “Journal of Dermatological Science” Researchers found a new area on chromosome 2 linked to a genetic hair loss condition.
11 citations
,
July 2010 in “European Journal of Dermatology” In this study, researchers confirmed linkage of a form of hair-nail ectodermal dysplasia to chromosome 12 in a Pakistani family, suggesting a possible non-coding mutation in KRTHB5 or a mutation in an unknown gene.
This study developed a method using ultra-performance liquid chromatography and mass spectrometry to detect illegal substances in hair loss prevention cosmetics, revealing that some products contained high levels of minoxidil and finasteride, posing safety risks.
143 citations
,
January 2007 in “The American Journal of Human Genetics” This study identified four genetic loci on chromosomes 6, 10, 16, and 18 that may contribute to susceptibility for alopecia areata and suggested shared genetic factors with psoriasis.
65 citations
,
April 2021 in “Natural Products and Bioprospecting” This review discusses the traditional uses and pharmacologically active compounds of 22 Dendrobium species for dermatological disorders but reports no new results, highlighting the need for further research.
61 citations
,
September 1994 in “Journal of Medical Genetics” This study found strong evidence linking a keratin gene anomaly to pachyonychia congenita, supporting its role in affecting skin, nails, hair, and mucosa.
54 citations
,
January 1995 in “Human Molecular Genetics” This study mapped monilethrix, a hereditary hair and nail disorder, to the type II keratin cluster on chromosome 12q, marking the first primary human hair disorder localization and implicating defects in "hard" keratins.
51 citations
,
January 2007 in “Animal Genetics” This study identified the location of the genetic locus for the slick hair coat trait in cattle on bovine chromosome 20, which may contribute to heat tolerance.
39 citations
,
July 1997 in “American Journal of Medical Genetics” This study confirmed linkage of Clouston syndrome in a large Indian family to the 13q11-12.1 region, suggesting it shares a genetic basis with French Canadian cases.
28 citations
,
March 2010 in “Clinics in dermatology” This review details historical advancements in understanding and treating superficial fungal infections, with notable milestones in identifying causative agents and developing effective treatments, but it reports no new findings.
13 citations
,
February 2006 in “Analytical Biochemistry” This study reported a simple and validated gas chromatography method to accurately measure finasteride in tablets, showing equivalency to the official method with no significant differences.
8 citations
,
January 2018 in “Journal of Analytical Methods in Chemistry” This study developed a reliable HPLC-UV/Vis method to determine aluminum phthalocyanine chloride in skin, supporting its use in skin permeation studies for photodynamic therapy of cutaneous tumors.
6 citations
,
March 2018 in “Journal of Chromatography A” This study describes an analytical technique combining field-enhanced sample stacking with dispersive liquid-liquid microextraction, offering improved sensitivity for detecting finasteride and its metabolite in urine samples from patients treated for androgenetic alopecia.
5 citations
,
October 2022 in “Heliyon” This review discusses infertility in polycystic ovary syndrome and therapeutic options, without reporting new results; it underscores the importance of personalized treatment plans based on patient needs and disease characteristics.
3 citations
,
July 2022 in “BMC chemistry” This study introduced and validated new spectrophotometric methods to simultaneously determine finasteride and tadalafil in Entadfi™ capsules with high sensitivity and without interference from excipients.
1 citations
,
July 2023 in “International Journal of Pharmaceutical Sciences and Drug Research” This study developed an effective and reliable HPTLC method for the simultaneous measurement of linoleic acid and oleanolic acid in Eclipta alba.