Determination of 19 Illegally Added Chemical Ingredients in Hair Loss Prevention Cosmetics by Ultra-Performance Liquid Chromatography-Quadrupole-Time of Flight Mass Spectrometry

    April 2022 in “ Sepu ”
    Ya-lei Dong, Shuijiao Niu, Yasen Qiao, Chuanfeng Huang, Haiyan Wang, Lei Sun
    TLDR A new method can quickly and accurately detect illegal chemicals in hair loss products.
    Researchers developed a method using ultra-performance liquid chromatography-quadrupole-time of flight mass spectrometry (UPLC-Q-TOF-MS) to detect 19 illegal chemical additives in hair loss prevention cosmetics. This method achieved separation within 20 minutes and demonstrated good linearity, with limits of detection (LODs) and quantification (LOQs) ranging from 0.025-0.05 μg/g and 0.075-0.15 μg/g, respectively. Recovery experiments showed average recoveries between 68.6% and 118.6%, with relative standard deviations (RSDs) of 0.3%-10.3%. Screening of 77 cosmetic samples identified two batches adulterated with high levels of minoxidil (60 mg/g) and finasteride (0.31 mg/g), posing significant safety risks. The method is noted for its simplicity, high sensitivity, and reproducibility, making it suitable for rapid screening and quantitative analysis of illegal chemicals in hair loss prevention products.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community 2 year fin/min progress (age 27-29)

      in Progress Pictures  302 upvotes 1 year ago
      A user's two-year progress using 1mg of oral finasteride daily and twice daily application of 5% minoxidil solution for hair loss. The user experienced temporary side effects but is pleased with the results, and another user warns about the importance of consistent use for maintaining results.

      community My Testosterone results before and after Finasteride

      in Update  146 upvotes 3 years ago
      Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

      community Nandrolone Replacement Therapy

      in Treatment  41 upvotes 1 year ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

      community Minoxidil&Finasteride 7 months progress

      in Progress Pictures  936 upvotes 11 months ago
      A user shared their 7-month progress using Minoxidil and Finasteride for hair loss, which significantly reversed their aging appearance. They applied Minoxidil twice daily, took 1mg Finasteride once daily, micro-needled weekly, maintained a high protein diet with vitamins and biotin, and recommended a balanced lifestyle for best results.

    Similar Research

    5 / 1000+ results