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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Excess androgens may cause PCOS, not just be a symptom.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Surgery is the main treatment for liver hydatidosis, but has risks; albendazole is the most effective drug but can have side effects.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Finasteride safely lowers DHT levels without affecting testosterone.

OM-X® helped prevent negative effects of Vitamin C deficiency in mice, suggesting it could protect organs and regulate metabolism.

Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.

Plant-based compounds can improve wound dressings and skin medication delivery.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Ayurvedic Panchakarma therapy, Virechan, can effectively manage PCOS symptoms and improve health markers.