August 2024 in “Veterinary Dermatology” Topical ceramide treatment partially improves the skin condition in Jack Russell Terriers with a genetic skin disorder.
[object Object] 489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
450 citations,
January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
182 citations,
November 2018 in “Cosmetics” Seaweeds have beneficial compounds for skin care, including anti-aging and protective effects.
119 citations,
December 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Nanoparticles can deliver vaccines through hair follicles, triggering immune responses and providing protection.
101 citations,
March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
95 citations,
July 2015 in “European journal of pharmaceutics and biopharmaceutics” Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
75 citations,
February 2017 in “Aging” SkQ1 antioxidant improved health and lifespan in mice.
73 citations,
April 2006 in “BioTechniques” Protein microarrays are highly sensitive tools useful for disease diagnosis and studying proteins.
61 citations,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
59 citations,
August 2021 in “Frontiers in Endocrinology” GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
46 citations,
January 2020 in “Research” Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
37 citations,
November 2017 in “Medical Sciences” Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
29 citations,
June 2020 in “International Journal of Molecular Sciences” Notch signaling disruptions can cause various skin diseases.
15 citations,
January 2023 in “Biomaterials Research” 3D bioprinting in plastic surgery could lead to personalized grafts and fewer complications.
12 citations,
May 2023 in “EMBO reports” High mTORC1 activity slows hair growth and causes it to lose color.
12 citations,
September 2022 in “Foods” Some nutraceuticals may help in COVID-19 prevention and treatment, but more research is needed.
12 citations,
January 2020 in “Analyst” Researchers found markers that can tell if hair has been bleached, which could improve hair test accuracy.
12 citations,
December 2010 in “Journal of thoracic oncology” New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.
[object Object] 11 citations,
October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
9 citations,
July 2021 in “Frontiers in Pharmacology” Cholesterol-modified siRNAs targeting certain genes increased hair growth in mice.
9 citations,
May 2021 in “BioMed research international” Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.
9 citations,
May 2021 in “Frontiers in aging neuroscience” Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.
8 citations,
May 2023 in “Gels” Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.
6 citations,
January 2023 in “International journal of molecular sciences” Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.
6 citations,
September 2021 in “Autophagy” Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.
4 citations,
December 2022 in “Frontiers in Bioengineering and Biotechnology” Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.
4 citations,
August 2021 in “Frontiers in Cell and Developmental Biology” Stress can cause hair loss by affecting nerve-related hair growth, and noradrenaline might help prevent this.
4 citations,
March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
3 citations,
June 2023 in “Molecules/Molecules online/Molecules annual” Cepharanthine has many medicinal uses but needs improvement for better effectiveness.