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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Men can have genetic risks for PCOS-related traits like obesity and diabetes.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Manage women's cholesterol with diet, exercise, and careful treatment choices, especially during pregnancy, PCOS, and menopause.

People with lichen planus are more likely to have dyslipidemia, especially higher triglyceride levels.

People with early onset baldness have higher bad cholesterol and lower good cholesterol, increasing their heart disease risk.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Polycystic Ovary Syndrome (PCOS) in teenagers is a complex condition linked to genetics and environment, often associated with obesity and insulin resistance, and is treated with lifestyle changes and medication.

Medications for PCOS don't seem to raise heart disease risk.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Patients with mycosis fungoides have a higher risk of heart disease.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Indian women with PCOS may need different ultrasound criteria for diagnosis than current standards.

The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

The document suggests more research is needed to understand the link between baldness and prostate cancer.

More than half of the women with PCOS in Southern India had Metabolic Syndrome, with large waist circumference being the most common feature.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.