Polycystic Ovary Syndrome in Adolescents

June 2019 in “ Best Practice & Research Clinical Endocrinology & Metabolism ”

Preeti Dabadghao

Polycystic Ovary Syndrome PCOS hyperandrogenism insulin resistance obesity menstrual irregularity

TLDR Polycystic Ovary Syndrome (PCOS) in teenagers is a complex condition linked to genetics and environment, often associated with obesity and insulin resistance, and is treated with lifestyle changes and medication.

The document from May 31, 2019, discussed Polycystic Ovary Syndrome (PCOS) in adolescents, a condition characterized by menstrual irregularity and hyperandrogenism, affecting 3.6-15% of women in the reproductive age group. The exact cause of PCOS was not known, but it was understood to be a complex disease resulting from a combination of genetic susceptibility, intrauterine, extra-uterine, and environmental factors. Obesity and insulin resistance were common associations, putting patients at high risk for metabolic and cardiovascular diseases. Diagnosing PCOS in adolescents was challenging due to the overlap of its clinical features with normal puberty. Treatment involved lifestyle modifications and pharmacological agents to control hyperandrogenism and menstrual disturbances.

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research Comprehensive Overview of Polycystic Ovary Syndrome

883 citations , August 2016 in “Nature Reviews Disease Primers”

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

research Epidemiology of Hirsutism Among Women of Reproductive Age in the Community: A Simplified Scoring System

37 citations , August 2012 in “European Journal of Obstetrics & Gynecology and Reproductive Biology”

A simplified scoring system can effectively diagnose hirsutism in Chinese women of reproductive age.

research Consensus on Women's Health Aspects of Polycystic Ovary Syndrome: The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group

1514 citations , January 2012 in “Fertility and sterility”

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

research The Diagnosis of Polycystic Ovary Syndrome in Adolescents

212 citations , September 2010 in “American Journal of Obstetrics and Gynecology”

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

research Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan

926 citations , June 2010 in “BMC Medicine”

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

research Visually Scoring Hirsutism

288 citations , June 2009 in “Human reproduction update”

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

research The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report

1540 citations , February 2009 in “Fertility and Sterility”

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

research Relative Prevalence of Different Androgen Excess Disorders in 950 Women Referred Because of Clinical Hyperandrogenism

352 citations , January 2006 in “The Journal of Clinical Endocrinology and Metabolism”

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

research Androgen Excess in Women: Experience with Over 1000 Consecutive Patients

947 citations , February 2004 in “The Journal of Clinical Endocrinology and Metabolism”

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS)

4025 citations , January 2004 in “Human Reproduction”

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.