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CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss in Discoid Lupus.

This article presents two cases of keratosis follicularis spinulosa decalvans and reviews its features, highlighting characteristic progression from keratosis pilaris in infancy to cicatricial alopecia in childhood.

A patient had both chronic lupus and systemic scleroderma, requiring careful treatment to manage symptoms.

This case report describes a family with autosomal dominant transmission of keratosis follicularis spinulosa decalvans, with observed treatment refractoriness in multiple topical and systemic therapies.

Topical latanoprost and bimatoprost ophthalmic solutions don't help eyelash growth in patients with alopecia areata.

This case report discusses a 58-year-old female diagnosed with oral lichen sclerosus, an extremely rare form of the disorder, which improved following treatment with topical and intralesional corticosteroids, highlighting the importance of recognizing this rare condition in the oral mucosa.

This case report presents a patient with necrobiosis lipoidica exhibiting transepithelial elimination of cholesterol crystals through hair follicles, a finding previously associated with necrobiotic xanthogranuloma.

This study identified biallelic variants in the LSS gene as a possible genetic cause of palmoplantar keratoderma-congenital alopecia syndrome type 2, highlighting the role of cholesterol synthesis in skin cornification.

This case report involves a 56-year-old woman with idiopathic thrombocytopenic purpura and scarring alopecia, suggesting diagnoses including discoid lupus erythematosus and lichen planopilaris without presenting new clinical findings.

This case report details a 12-year-old boy with Lichen Spinulosus and plantar keratoderma, who responded well to topical treatments including lactic acid, urea, and betamethasone valerate.

In this study, researchers found that the compound BMS-470539 induced a senescence-like state in fibroblasts from systemic sclerosis patients, reducing fibrosis-associated markers in vitro and decreasing skin thickness in a mouse model of skin fibrosis, suggesting a novel therapeutic strategy for managing fibroblast-driven diseases.

Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.

This study suggests that macrophages play a more substantial role in the pathogenesis of Lichen planopilaris compared to Frontal fibrosing alopecia, as indicated by increased CD68+ cells in Lichen planopilaris.

This study found that in mice, high-fat diets quickly reduce the skin's ability to transfer heat, while diets preventing obesity increase skin energy loss, suggesting the skin plays an active role in energy metabolism and lipid regulation.

This study found that skin changes in morbidly obese individuals are associated with underlying metabolic disturbances but are not currently valuable as independent tools for assessing metabolic risk or treatment response.

This study suggests that pseudopelade may be an autonomous disease based on its distinctive clinical and histopathological features not present in other scarring alopecias.

Discoid lupus erythematosus involves immune activation and fibrosis around hair follicles, with shared pathways across humans, dogs, and mice, suggesting potential treatments for both humans and animals.

PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.

This case report describes a 47-year-old patient with scarred alopecia diagnosed as discoid lupus erythematosus, where treatment with multiple medications led to clinical improvement.

This report describes two cases of nevus lipomatosus superficialis with the unusual feature of dilated hair follicles, emphasizing the need for precise histopathological diagnosis to differentiate from similar conditions.

In this case report, a rare instance of Graham–Little–Piccardi–Lassueur syndrome coexisting with linear lichen planus was identified in a 35-year-old male, highlighting the condition's rarity in males, with dermoscopy aiding diagnosis through distinctive scalp and trunk lesion features.

This review highlights that metabolic syndrome is intricately linked with various skin conditions such as inflammatory skin diseases and tumors through mechanisms involving insulin resistance and chronic inflammation, aiming to guide clinicians on effective treatments and preventive strategies for affected patients.

In this case report, an 11-year-old girl was diagnosed with lipedematous scalp, a condition typically observed in adult women, based on clinical features and histopathological findings.

This case report describes a patient with untreated lepromatous leprosy developing Lucio's phenomenon, highlighting difficulties in distinguishing it from erythema nodosum leprosum with vasculonecrotic lesions.

This case report documents a 10-year-old girl with keratosis follicularis spinulosa decalvans, highlighting its rarity, particularly in females, and noting limited treatment success.

This manuscript reports on the first case of perforating necrobiosis lipoidica in Colombia, marking the 19th documented case worldwide.

This study observed that finasteride treatment induced mild improvement in androgenetic alopecia in one male patient while stabilizing the condition in another, but lipedematous scalp remained unchanged.

Suplatast tosilate successfully treated a woman's systemic sclerosis symptoms.

This case report describes a Taiwanese woman with lipedematous alopecia, highlighting rare mucin deposition as a feature that warrants further investigation.

This case report details a 37-year-old woman with pityriasis rubra pilaris, highlighting scarring alopecia and widespread hyperkeratotic lesions despite various treatments.