Chronic Lupus Erythematosus and Systemic Scleroderma Coexistent in the Same Patient

January 2018 in “ ARC Journal of Dermatology ”

Rosa Giménez‐García, Donna Zhan, Diego González González, Daniel Colinas-Reyero

chronic lupus erythematosus systemic scleroderma inflammatory alopecia telangiectasia Raynaud phenomenon antimalarials vasodilators azathioprine biological therapies corticosteroids

TLDR A patient had both chronic lupus and systemic scleroderma, requiring careful treatment to manage symptoms.

The document presented a case study of a 50-year-old patient diagnosed with both chronic lupus erythematosus and systemic scleroderma, illustrating an overlap syndrome. The patient exhibited symptoms such as inflammatory alopecia plaques, lesions on the palate, and telangiectasia on the palms. Biopsies confirmed chronic lupus, and capillaroscopy indicated Raynaud phenomenon, suggesting scleroderma. The pulmonary CT scan showed honeycombing in the lungs, a common scleroderma manifestation. Treatment included antimalarials, vasodilators, and azathioprine. The study highlighted the importance of distinguishing between scleroderma renal crisis and lupus nephritis due to differing treatments and suggested that new biological therapies could reduce the need for high-dose corticosteroids.

View this study on doi.org →

Discuss this study in the Community →

Research cited in this study

1 / 1 results

research Chronic Lupus Erythematosus and Systemic Scleroderma Coexistent in the Same Patient

1 citations , January 2018 in “ARC Journal of Dermatology”

A patient had both chronic lupus and systemic scleroderma, requiring careful treatment to manage symptoms.

Related Community Posts Join

6 / 384 results

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community My experience with 0.25mg Finasteride, Minoxidil induced lupus, and < 10mg RU58841.

in Treatment 8 upvotes 4 years ago

MaximusDurkimus shares experience with 0.25mg Finasteride, Minoxidil-induced lupus, and less than 10mg RU58841 for hair loss. Plans to try 0.025% topical Finasteride with 5% Stemoxydine and possibly Tretinoin, Fluridil, or CB-03-01 in the future.

community What other factors than DHT causes hair loss – and what to do about it?

in Treatment 3 years ago

Factors that can cause hair loss other than DHT, such as inflammation and diet, and potential treatments like scalp massages, minoxidil, citrulline, stretches, meditation, iron sulfate/Vitamin C, Vitamin D, protein and Dutasteride.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 10 months ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community Minoxidil Finasteride heart problems

in Update 97 upvotes 1 year ago

A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.

community How is it possible for someone to be a non responder to ORAL minoxidil?

in Minoxidil 66 upvotes 1 year ago

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.