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    Did you mean Chronic Cutaneous Lupus Erythematosus?
    GlossaryDiscoid Lupus Erythematosus (Chronic Cutaneous Lupus Erythematosus)

    chronic autoimmune condition causing red, scaly skin patches

    Discoid Lupus Erythematosus (DLE) is a chronic autoimmune condition that primarily affects the skin, leading to the development of red, inflamed, and scaly patches, often on the face, scalp, and ears. These lesions can cause scarring and permanent hair loss if they occur on the scalp.

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      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fin/dut increase in estrogen and autoimmune diseases

      in Chat  7 upvotes 2 years ago
      The conversation discusses the link between increased estrogen and autoimmune diseases, with a focus on avoiding soy and milk. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

      community Seeking Advice: Unusual Hair Loss at 31 Years Old - Any Insights? (M)

      in Chat  15 upvotes 1 year ago
      A 31-year-old man who previously had good results with minoxidil, finasteride, and nizoral for hair loss is now experiencing unusual hair loss and side effects from finasteride. Respondents suggest it might be severe retrograde alopecia and recommend exploring other treatment options due to his inability to tolerate finasteride.