Lupus Panniculitis as an Initial Manifestation of Systemic Lupus Erythematosus: A Case Report

    August 2019 in “ Blucher Medical Proceedings
    MÔNICA MÂNICA, Gustavo Nogueira, Luana Cocco Garlet, ANDREIA SILVA ROSA, ALESSANDRA PANOSSO SCHAFER, Emanuela Lando, GUILHERME CASA, CAROLINA BRIZOLA, Julia Bianchi, HENRIQUE ZIELKE, Bruna Dambrós Neckel, MOARA ALDROVANDI, Daniela Ragnini, M Pedro Magalhães, Carolina Silva, FRANCIELI PARIZOTTO, GUILHERME CENTENARO, Thaís Rohde Pavan
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    TLDR Lupus Panniculitis can be an early sign of Systemic Lupus Erythematosus.
    Systemic Lupus Erythematosus (SLE) is a chronic inflammatory disease that often involves the skin, leading to its inclusion in the diagnostic criteria. Lupus Panniculitis (LP), a rare form of Chronic Cutaneous Lupus Erythematosus (CCLE), affects 1-3% of patients and can occur alone or with SLE or Discoid Lupus Erythematosus. LP is characterized by a T-lymphocyte-mediated autoimmune response, with histopathological studies showing lobular or mixed panniculitis and a significant lymphocytic infiltrate at the dermis-epidermal junction.
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