Bilateral Periorbital Erythema and Swelling as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case
April 2025
in “
Current Rheumatology Reviews
”
Studysummary This case study highlights the importance of considering systemic lupus erythematosus in young patients presenting with atypical symptoms like periorbital erythema and pancytopenia, as early diagnosis and treatment can lead to remission.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
This case study describes a 16-year-old girl with systemic lupus erythematosus (SLE) who presented with atypical symptoms of bilateral periorbital swelling and localized alopecia. Despite normal renal, hepatic, and thyroid functions, laboratory tests revealed pancytopenia and elevated autoimmune markers, leading to an SLE diagnosis. Treatment with methylprednisolone and hydroxychloroquine resulted in significant improvement, including resolution of swelling and hair regrowth. The case emphasizes the importance of recognizing atypical SLE presentations for early diagnosis and effective treatment to prevent complications.
