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    Glossary Chronic Leg Ulcers

    long-lasting leg sores that don't heal within six weeks

    Chronic leg ulcers are long-lasting sores or wounds on the legs that fail to heal within a typical timeframe, usually defined as six weeks or more. They are often caused by underlying conditions such as poor blood circulation, diabetes, or venous insufficiency, and can lead to significant pain, infection, and reduced quality of life if not properly managed.

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    1. Skin grafting for the treatment of chronic leg ulcers – a systematic review in evidence‐based medicine International Wound Journal · 2016 · 56 citations
    2. Klinefelter syndrome and chronic leg ulcers Journal of The American Academy of Dermatology · 2009
    3. Successful Treatment of Chronic Leg Ulcers with Epidermal Equivalents Generated from Cultured Autologous Outer Root Sheath Cells Journal of Investigative Dermatology · 1996 · 99 citations
    4. A pilot clinical study of hair grafting in chronic leg ulcers Wound Repair and Regeneration · 2012 · 63 citations
    5. Autologous smashed follicular dermal graft with epidermal cell suspension in chronic nonhealing leg ulcers Journal of Cutaneous and Aesthetic Surgery · 2020 · 3 citations
    6. Hair-follicle Transplant Into Chronic Ulcers: A New Graft Concept 2017 · 6 citations
    7. Ankle Range of Motion, Leg Pain, and Leg Edema Improvement in Patients With Venous Leg Ulcers JAMA Dermatology · 2016 · 4 citations
    8. Regeneration of Chronic Wounds with Allogeneic Platelet Gel versus Hydrogel Treatment: a Prospective Study Acta Clinica Croatica · 2018 · 25 citations
    9. Topical application of cellulose membrane for the treatment of non-healing venous leg ulcers Frontiers in Bioengineering and Biotechnology · 2026
    10. Hair follicle stem cells: Walking the maze European Journal of Cell Biology · 2007 · 165 citations
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