Successful Treatment of Chronic Leg Ulcers with Epidermal Equivalents Generated from Cultured Autologous Outer Root Sheath Cells
July 1996
in “
Journal of Investigative Dermatology
”
Research cited in this study
8 / 8 resultsresearch Proliferation and Differentiation of Cultured Human Follicular Keratinocytes Are Not Influenced by Biotin
research Formation of a Regular Neo-Epidermis by Cultured Human Outer Root Sheath Cells Grafted on Nude Mice
Human hair follicle cells can be used to help heal and replace skin.
research Effects of 1α,25-Dihydroxy-Vitamin D3 and Calcipotriol on Organotypic Cultures of Outer Root Sheath Cells: A Potential Model to Evaluate Antipsoriatic Drugs
Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.
research Soluble Factors From Human Hair Papilla Cells And Dermal Fibroblasts Dramatically Increase The Clonal Growth Of Outer Root Sheath Cells
research Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells
ORS and hair matrix cells balance growth and differentiation better than normal keratinocytes, with human dermal fibroblasts crucial for proper differentiation.
research Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro
Outer root sheath cells consistently express certain keratins influenced by their environment.
research Growth of Human Hair Follicle Keratinocytes In Vitro
research A Method for Culturing Human Hair Follicle Cells
The document described a pioneering method for culturing human hair follicle cells using the bovine eye lens capsule as a substrate. This approach allowed for the formation of growing colonies of diploid keratinocytes in a culture medium supplemented with hydrocortisone and insulin, with approximately 70% of the original follicles successfully forming these colonies.
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