chodroitin sulfete
Research
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research A Dynamically Crosslinked, Self-Adapting, Injectable Gelatin–Chondroitin Sulfate Hydrogel With Antibacterial and Antioxidant Properties for Treatment of Deep and Irregular Wounds
In this study, researchers developed a multifunctional, injectable hydrogel that adapts to irregularly shaped wounds, enhances healing, and shows potential antibacterial activity without significant toxicity, suggesting promise for treating chronic wounds.
research Fetal Environment-Simulating Hyaluronic Acid-Dopamine-Chondroitin Sulfate Hydrogel Promoting Angiogenesis and Hair Regeneration for Wound Healing
In this study, the researchers developed a hydrogel mimicking the fetal environment that significantly accelerated wound healing and hair follicle regeneration in vivo, with over 94% wound closure in 14 days, surpassing hydrogels lacking certain additives.
research Vascularization of Skin Substitute Constructed by Vascular Endothelial Growth Factor 165 Gene-Modified Hair Follicle Stem Cells Compounded with Three-Dimensional Gelatin-Chondroitin Sulfate-Hyaluronic Acid
This study found that a modified scaffold with VEGF165 genetically modified hair follicle stem cells significantly promoted blood vessel growth and wound healing in rats, suggesting its potential as a skin substitute in clinical settings.
research Gelatin-Chondroitin-6-Sulfate-Hyaluronic Acid Scaffold Seeded with Vascular Endothelial Growth Factor 165 Modified Hair Follicle Stem Cells as a Three-Dimensional Skin Substitute
This study found that using 3D Gel-C6S-HA scaffolds seeded with VEGF165-modified rat hair follicle stem cells enhanced angiogenesis and vascularization in tissue-engineered skin, improving wound healing.
research Epidermal and Hair Follicle Progenitor Cells Express Melanoma-Associated Chondroitin Sulfate Proteoglycan Core Protein
MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.
research Structural Characterization and Wound Healing Activity of Sulfated Glycosaminoglycans from Acipenser Baerii Cartilage: Potential Regulation of Fibroblast Function
In this study on wound healing, sulfated glycosaminoglycans from sturgeon cartilage enhanced fibroblast cell proliferation, migration, and collagen deposition, significantly accelerating wound closure and promoting re-epithelialization in both in vitro and in vivo tests.
research Dynamic Expression Patterns of Tenascin, Proteoglycans, and Cell Adhesion Molecules During Human Hair Follicle Morphogenesis
This study analyzed the distribution of adhesion molecules and extracellular matrix components in human fetal skin, suggesting their roles in hair follicle development.
research Evidence for Multiple, Developmentally Regulated Isoforms of Ptprq on Hair Cells of the Inner Ear
This study suggests that Ptprq in the hair bundles may exist as multiple isoforms that are differentially expressed throughout development and affect the organization of stereocilia in the chick inner ear.
research Activation of Astrocytes In Vitro by Macrophages Polarized with Keratin Biomaterial Treatment
This study found that macrophages treated with keratin in vitro were more similar to anti-inflammatory M2 macrophages and reduced astrocyte reactivity, potentially limiting secondary inflammatory damage after spinal cord injury.
research Upcycling Eggshell Matrix for Sustainable Production of Glycosaminoglycans
This review explores the eggshell matrix as a potential sustainable and cost-effective alternative source for glycosaminoglycans, but highlights the need for further research to enhance extraction techniques and economic viability.
research Isolating Subpopulations of Human Epidermal Basal Cells Based on Polyclonal Serum Against Trypsin-Resistant CSPG4 Epitopes
This study reveals that CSPG4-positive basal cell keratinocytes show distinct global gene expression from CSPG4-negative cells, despite similar colony-forming efficiency.
research Relapsing Polychondritis Following Alopecia Areata
This case report and literature review explore a potential immunological link between alopecia areata and relapsing polychondritis, suggesting that the latter might be a systemic manifestation of the former.
research A Dietary Supplement Improves Age-Related Dermatological Changes: Observational, Anecdotal, Spontaneous Study
This study found that dietary supplementation with collagen, chondroitin sulfate, low-molecular weight hyaluronic acid, Pycnogenol®, and coenzyme Q10 significantly improved skin hydration, elasticity, nail hardness, and hair condition in patients with age-related dermatological changes after 12 weeks.
research Reprogramming Wound Healing: GAG-Based Bioactive Scaffold Drives Pro-Regenerative Cellular Cross-Talk
This study found that a chitosan, chondroitin sulfate, and hyaluronic acid scaffold improved wound healing in rats by promoting immune-stromal interactions, reducing inflammation, and supporting tissue regeneration with ~91% wound closure by day 17 compared to ~63% in controls.
research Production of Glycosaminoglycans by Rat Hair Follicle Cells In Vitro
This study observed that rat dermal tissue cultures, rich in hair follicle cells, produce various glycosaminoglycans, including hyaluronic acid and dermatan sulfate, which change in synthesis and sulfation patterns over time.
research Design of an Artificial Skin. IV. Use of Island Graft to Isolate Organ Regeneration from Scar Synthesis and Other Processes Leading to Skin Wound Closure
This study found that island grafting in guinea pigs enabled the isolated study of early skin regeneration processes, distinguishing them from natural wound closure mechanisms like epithelialization and contraction.
research Hypersensitivity Reactions to Anticoagulant Drugs
This review discusses hypersensitivity reactions to anticoagulants like ASA and heparins, highlighting their rare but potentially life-threatening nature, and emphasizes the need for meticulous allergy testing to find safe alternatives.
research Electrophoretic Studies of Acid Mucopolysaccharides in Skin, Prekeratin of Hair Follicles, and Keratoses of Wool
This study found that chondroitin sulfate levels were higher than hyaluronic acid in skin and hair follicle samples, with the highest concentration observed in prekeratin of hair follicles and wool fibers.
research In Vitro 3D Organotypic Hair Follicle Model for High-Throughput Substance Testing
The researchers reported that hydrogels made from methacrylated glycol chitosan and hyaluronic acid with chondroitin sulfate may be suitable for load bearing soft tissue repair, showing enhanced chondrocyte viability and metabolic activity.
research Versican Expression by Dermal Papilla-Regenerated Hair Follicles: A Promising Tool for Hair-Regrowth Products
This study demonstrated that the large molecule versican plays a critical role in hair induction in dermal papilla cells, with potential implications for developing new hair growth treatments.