Chronic Cutaneous Lupus Erythematosus Presenting as Atypical Acneiform and Comedonal Plaque: Case Report and Literature Review

August 2017 in “ Lupus ”

Marcelo L. Vieira, Everaldo R. Marques, Y L A Leda, Leandro Fonseca Noriega, Diego Leonardo Bet, Gilmayara Alves Abreu Maciel Pereira

chronic cutaneous lupus erythematosus CCLE acneiform eruption comedonal plaque isotretinoin prednisone chloroquine diphosphate biopsy acne acneiform lesions acne treatments

TLDR Chronic cutaneous lupus erythematosus should be considered when acne treatments don't work.

This document described a case of chronic cutaneous lupus erythematosus (CCLE) presenting as atypical acneiform and comedonal lesions in a 32-year-old woman. The patient had been treated unsuccessfully for acne before a biopsy confirmed CCLE. Treatment with prednisone and chloroquine diphosphate led to significant improvement. A literature review identified nine other cases of acneiform lupus erythematosus, highlighting the rarity and diagnostic challenge of this presentation. The study emphasized the importance of considering CCLE in cases of treatment-resistant acneiform lesions, particularly when localized and itchy.

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research Overview of Common, Rare, and Atypical Manifestations of Cutaneous Lupus Erythematosus and Histopathological Correlates

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The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

research Discoid Lupus Erythematosus Presenting with Cysts, Comedones, and Cicatricial Alopecia on the Scalp

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research Comedonal Lupus: A Case Study of a 60-Year-Old Moroccan Man

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Chronic Cutaneous Lupus Erythematosus Presenting as Atypical Acneiform and Comedonal Plaque: Case Report and Literature Review

Research cited in this study

research Overview of Common, Rare, and Atypical Manifestations of Cutaneous Lupus Erythematosus and Histopathological Correlates

research Discoid Lupus Erythematosus Presenting with Cysts, Comedones, and Cicatricial Alopecia on the Scalp

research Comedonal Lupus: A Case Study of a 60-Year-Old Moroccan Man

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