Chronic Cutaneous Lupus Erythematosus Presenting as Atypical Acneiform and Comedonal Plaque: Case Report and Literature Review

August 2017 in “ Lupus ”

Marcelo L. Vieira, Everaldo R. Marques, Y L A Leda, Leandro Fonseca Noriega, Diego Leonardo Bet, Gilmayara Alves Abreu Maciel Pereira

chronic cutaneous lupus erythematosus CCLE acneiform eruption comedonal plaque isotretinoin prednisone chloroquine diphosphate biopsy acne acneiform lesions acne treatments

Studysummary This case report and literature review highlights an unusual acne-like presentation of chronic cutaneous lupus erythematosus that doesn't improve with standard acne treatments, emphasizing the importance of considering CCLE in atypical acneiform eruptions.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This document described a case of chronic cutaneous lupus erythematosus (CCLE) presenting as atypical acneiform and comedonal lesions in a 32-year-old woman. The patient had been treated unsuccessfully for acne before a biopsy confirmed CCLE. Treatment with prednisone and chloroquine diphosphate led to significant improvement. A literature review identified nine other cases of acneiform lupus erythematosus, highlighting the rarity and diagnostic challenge of this presentation. The study emphasized the importance of considering CCLE in cases of treatment-resistant acneiform lesions, particularly when localized and itchy.

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research Overview of Common, Rare, and Atypical Manifestations of Cutaneous Lupus Erythematosus and Histopathological Correlates

157 citations , August 2010 in “Lupus”

This review discusses the various common, rare, and unusual skin manifestations of lupus erythematosus and highlights the importance of accurate diagnosis, but it reports no new clinical results.

research Discoid Lupus Erythematosus Presenting with Cysts, Comedones, and Cicatricial Alopecia on the Scalp

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research Comedonal Lupus: A Case Study of a 60-Year-Old Moroccan Man

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A man was diagnosed with a rare form of lupus after showing unique skin symptoms that responded well to treatment.