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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

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      community Bryan Johnson and his Hair routine, what's the point?

      in Hair Systems  8 upvotes 1 day ago
      Dutasteride and high-dose Minoxidil are the primary treatments maintaining hair, with additional supplements and therapies like red light offering minimal extra benefit. The discussion criticizes promoting expensive hair care products when basic medications are doing most of the work.

      community Genomic Sequencing for Hair Loss

      in Research/Science  156 upvotes 6 days ago
      Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

      community Just found out my dad is not my dad and my bio dad is bald

      in Chat  73 upvotes 5 months ago
      A person is struggling with hair loss and mental health issues, using treatments like dutasteride and minoxidil, and planning a hair transplant. They recently discovered their biological father is bald, causing additional stress, but are encouraged by others to focus on their treatment success and seek professional help for their mental health.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.