research Targeted Therapy in Melanoma
New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.
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research Becker Nevus Syndrome
The document reports the first Brazilian case of a girl with Becker nevus syndrome, characterized by skin changes, breast underdevelopment, and scoliosis.
research Exfoliative Cutaneous Lupus Erythematosus in German Shorthaired Pointer Dogs: Disease Development, Progression, and Evaluation of Three Immunomodulatory Drugs (Ciclosporin, Hydroxychloroquine, and Adalimumab) in a Controlled Environment
Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.
research Focal Hypertrichosis During Topical Tacrolimus Therapy for Childhood Vitiligo
An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
research Analysis of the FGF Gene Family Provides Insights into Aquatic Adaptation in Cetaceans
Whale genes show changes that help them live in water, like less hair and better flippers.
research Clinical and Microscopic Features of Generalized Discoid Lupus Erythematosus in Dogs (10 Cases)
Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.
research Cutaneous Manifestations of Metabolic Diseases: Uncommon Presentations
Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.
research Pseudoxanthoma-Like Late-Onset Focal Dermal Elastosis
A woman had a skin condition with increased normal elastic fibers, not related to other known disorders, likely due to aging.
research Derma Rollers in Therapy: The Transition from Cosmetics to Transdermal Drug Delivery
Derma rollers show promise for skin improvement and drug delivery, but more research is needed on their safety and effectiveness.
research Cronkhite–Canada Syndrome: From Clinical Features to Treatment
There is no standard treatment for the rare Cronkhite–Canada syndrome, which can be fatal and lead to cancer.
research Effect of Nutritional Restriction on the Hair Follicles Development and Skin Transcriptome of Chinese Merino Sheep
Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.
research Platelet-Rich Plasma: Principles and Applications in Plastic Surgery
Platelet-rich plasma is beneficial in various plastic surgery applications, but more research is needed to standardize its use.
research Insights into the Regeneration of Skin from Acomys, the Spiny Mouse
The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.
research Persistent Major Alopecia Following Adjuvant Docetaxel for Breast Cancer: Incidence, Characteristics, and Prevention with Scalp Cooling
Scalp cooling effectively prevents severe hair loss in breast cancer patients treated with docetaxel and is safe.
research Msx2 Supports Epidermal Competency During Wound-Induced Hair Follicle Neogenesis
The gene Msx2 is crucial for hair follicle regeneration during wound healing.
research Any Route for Melanoblasts to Colonize the Skin
Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.
research Skin Manifestations of Chronic Kidney Disease
Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.
research Drug Reaction With Eosinophilia and Systemic Symptoms and Severe Involvement of Digestive Tract: Description of Two Cases
Severe digestive issues in DRESS need early endoscopy for better treatment.
research Topical Absorption and Systemic Toxicity
Some chemicals absorbed through the skin can cause serious health problems.
research Human Papillomavirus E6/E7 Oncogenes Promote Mouse Ear Regeneration by Increasing the Rate of Wound Re-Epithelization and Epidermal Growth
HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.
research Sarcoptic Mange in Three Alpacas Treated Successfully with Amitraz
Amitraz effectively treated sarcoptic mange in three alpacas.
research The Modern Management of Hirsutism
Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.
research Tamoxifen-Induced Total Alopecia
Tamoxifen can cause total hair loss but its benefits outweigh this side effect.
research Leucaena Leucocephala: A Nutritional Profile
Leucaena leucocephala is nutritious but needs careful processing to remove toxins.
research Hair Shaft Dysplasias
Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research Transcriptomic Regulation of Seasonal Coat Color Change in Hares
Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.
research Evaluation of the Efficacy of Transdermal Drug Delivery of Calcipotriol Plus Betamethasone Versus Tacrolimus in the Treatment of Vitiligo
Calcipotriol plus betamethasone with microneedling works better than tacrolimus for treating vitiligo.
research The Incidence and Management of Cutaneous Adverse Events of the Epidermal Growth Factor Receptor Inhibitors
EGFR inhibitors can cause various skin issues during cancer treatment, and managing these is important for patient care.
research Body Hair Transplant by Follicular Unit Extraction: My Experience With 122 Patients
Body hair transplantation is an effective method for restoring hair in people with severe baldness and limited scalp donor hair.