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Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Different types of skin cells play specific roles in development, healing, and cancer.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Estrogen therapy can reduce skin aging but has cancer risks.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Different types of stem cells and their environments are key to skin repair and maintenance.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

Ginseng is possibly safe but its effectiveness is unclear due to poor quality studies and mixed results.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Lower SHBG levels may increase the risk of PCOS.

Mutant mice help researchers understand hair growth and related genetic factors.

Women with PCOS are more likely to suffer from depression, anxiety, and stress.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.