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Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.

Melatonin improves cashmere goat hair quality by increasing follicles and reducing skin aging.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Keratin 79 is linked to liver damage and may help diagnose liver diseases.

Vitamin D Receptor is crucial for normal skin and hair growth.

Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.

Melatonin directly affects mouse hair follicles and may influence hair growth.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Hair follicles help attract immune cells to the skin during stress.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.

Finasteride may affect male fertility by interfering with specific sperm signaling.

The article concludes that creating a detailed map of normal human skin at the single-cell level is important.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.

Lower SMAD2/3 activation predicts more severe skin cancer.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Early genetic testing and JAK inhibitors can help treat systemic inflammation in SAVI patients.

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.

The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.

A new compound, 3a, effectively fights prostate cancer better than finasteride.