26 citations
,
June 2024 in “Frontiers in Immunology” The authors discussed that SOCS1 and SOCS3's inhibition of JAKs plays a significant role in the development of JAK inhibitor drugs for skin inflammatory diseases and malignancies.
July 2025 in “Case Reports in Dermatology” This case report highlights that early signs like pili torti may precede lichen planopilaris in some patients, emphasizing the importance of timely intervention to prevent permanent hair loss.
February 2026 in “Indian Dermatology Online Journal” This study reports that oral tofacitinib treatment in a patient with refractory lichen planus pigmentosus and frontal fibrosing alopecia resulted in near-complete resolution of hyperpigmentation and cessation of hairline recession over 18 months, and suggests it may be a promising therapy for these challenging conditions.
105 citations
,
December 2009 in “Archives of dermatology” This overview discusses primary cicatricial alopecias, focusing on lichen planopilaris, and highlights the challenges in treatment and the progressive nature of hair loss despite symptom management, without providing new clinical results.
January 2022 in “Clinical Cases in Dermatology” This review describes lichen planopilaris diffuse pattern and recommends topical corticosteroids as a first-line treatment, but reports no new clinical results.
5 citations
,
January 2017 in “Chalmers Publication Library (Chalmers University of Technology)” In this study, cubosome and hexosome carriers with antimicrobial peptides showed varied efficacy, with cubosomes protecting peptides from degradation and enhancing bactericidal effects in some cases, while hexosomes lacked antimicrobial activity.
90 citations
,
July 2008 in “Dermatologic therapy” This article reviews lichen planopilaris, a chronic scarring alopecia, and explores recent treatment developments, but it reports no new clinical results.
June 2026 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This study concluded that oral tofacitinib significantly improved symptoms in patients with lichen planus pigmentosus who did not respond to conventional treatments, showing it as a viable alternative.
This article discusses folliculitis decalvans as a cicatricial alopecia caused by a neutrophilic immune reaction to microbial biofilms, but it reports no new clinical results.
2 citations
,
June 2016 in “Oral Surgery Oral Medicine Oral Pathology and Oral Radiology” This study reports the first known case of oral lichen planus preceding lichen planopilaris in a patient, highlighting a possible sequential relationship between the conditions.
3 citations
,
January 2016 in “Dermatology online journal” This review discusses the potential relationship between lichen planus pigmentosus and frontal fibrosing alopecia, presenting a case study but reporting no new clinical findings.
5 citations
,
January 2018 in “Indian Dermatology Online Journal” This case report describes a strong dermoscopic and histopathological correlation in lichen nitidus, helping differentiate it from other similar conditions.
April 2026 in “International Journal of Research in Dermatology” This meta-analysis found that laser-based therapies showed promising clinical benefits in treating scarring alopecias, such as disease stabilization and symptom improvement, but highlighted the need for high-quality randomized controlled trials due to serious risk of bias and methodological limitations in existing studies.
This study found a significant discordance between clinical symptoms and dermatoscopic signs with histopathological inflammation in patients with LPP and AFF, affecting diagnostic and therapeutic approaches.
February 2024 in “International Journal For Multidisciplinary Research” This review examines the advances in nanostructured lipid carriers for treating hyperpigmentation but presents no new clinical results; the authors highlight their potential benefits and applications.
39 citations
,
November 2017 in “PubMed” This case series reported that low-dose naltrexone may benefit patients with lichen planopilaris by reducing scalp symptoms and slowing disease progression, with no adverse effects observed in the patients.
3 citations
,
February 2024 in “Journal of the American Academy of Dermatology” This source discusses that while oral JAK inhibitors are used for treating lichen planopilaris and frontal fibrosing alopecia, they carry significant risk of adverse events; two cases showed promising results using tofacitinib cream as a safer topical alternative.
August 2017 in “International Journal of Research in Dermatology” This study found no significant association between metabolic syndrome and lichen planus, but hypertension, triglycerides, and low HDLC levels were significantly associated with lichen planus.
This report describes two cases where lichen planopilaris compromised hair follicles in both donor and recipient areas after follicular unit transplantation, emphasizing the need for a biopsy if lichen planopilaris is suspected.
49 citations
,
July 2007 in “Ophthalmic Plastic and Reconstructive Surgery” This report describes a case of granulomatous reaction to injectable poly-L-lactic acid in the periorbital area and suggests surgical excision as an effective treatment for persistent nodules.
November 2023 in “The actual problems in dentistry” This review of 48 scientific sources identifies various treatment methods, including drug and non-drug approaches, for oral lichen planus, highlighting side effects and emphasizing the need for more effective and personalized treatments due to existing contraindications, especially in severe cases.
June 2024 in “Cermin Dunia Kedokteran” This review discusses the benefits and applications of low level laser therapy in cosmetic dermatology, particularly for skin conditions and pigmentation disorders, but reports no new clinical results.
4 citations
,
April 2024 in “Clinical Cosmetic and Investigational Dermatology” This review examines the trichoscopic characteristics of scalp DLE and LPP, correlating these findings with histopathological data, but provides no new clinical results.
February 2010 in “Journal of the American Academy of Dermatology” Lactic acid cream can help improve skin bumps known as eruptive vellus hair cysts.
August 2025 in “Annals of African Medicine”
July 2024 in “Scholars Journal of Medical Case Reports” This study highlights examples of successful hair growth using combined laser therapy and autologous exosome therapy, suggesting a synergistic effect that may enhance beauty treatments and other therapeutic applications.
29 citations
,
February 2016 in “International Journal of Dermatology” This study found that patients with lichen planus were significantly more likely to have dyslipidemia, particularly with higher triglyceride levels.
July 2024 in “Journal of Investigative Dermatology” INTASYL is a promising, adaptable RNAi technology for treating skin cancers.
26 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the basics of hair follicle biology, laser/tissue interactions, and hirsutism and hypertrichosis causes, discussing the long-pulsed alexandrite laser's role in hair reduction without reporting new clinical results.
January 2022 in “Clinical Cases in Dermatology” This article discusses the causes and treatment options for lichen planopilaris, a scarring hair loss condition, but reports no new clinical findings.