Novel Treatment Using Low-Dose Naltrexone for Lichen Planopilaris

    November 2017 in “ PubMed ”
    Lauren C. Strazzulla, Lorena Avila, Kristen Lo Sicco, Jerry Shapiro
    TLDR Low-dose naltrexone helps reduce symptoms and slow down lichen planopilaris without side effects.
    The document described a retrospective medical record review of four patients with lichen planopilaris (LPP) treated with low-dose naltrexone (3 mg/day). The treatment resulted in reduced symptoms of pruritus, clinical evidence of scalp inflammation, and disease progression. All patients tolerated the medication well without adverse effects. This case series was the first to demonstrate the beneficial effects of low-dose naltrexone for LPP, highlighting its potential as a well-tolerated and cost-effective treatment option.
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