88 citations,
August 2014 in “PLOS genetics” Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
75 citations,
February 2017 in “Aging” SkQ1 antioxidant improved health and lifespan in mice.
4 citations,
October 2022 in “Nutrients” Personalized diets, like the Mediterranean Diet and low carb diets, can help manage PCOS symptoms in obese women, and probiotics may enhance weight loss and improve metabolic health. More research is needed to find the best diet strategies.
4 citations,
March 2018 in “Systems biology in reproductive medicine” Men born very underweight had higher estrogen levels but normal reproduction compared to normal birth weight men.
3 citations,
March 2022 in “Transgender Health” More research is needed to improve lower body gender affirmation techniques.
2 citations,
February 2023 in “BMC women's health” Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.
2 citations,
December 2022 in “Journal of Clinical Medicine” Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.
1 citations,
February 2023 in “Animals” 400 citations,
January 2014 in “British Journal of Sports Medicine” The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.
146 citations,
September 2013 in “Advances in nutrition” Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.
103 citations,
December 2021 in “Journal of biological rhythms” Shift work disrupts the body's natural clock, leading to health problems.
89 citations,
March 2001 in “Endocrine practice” The guidelines help doctors diagnose and treat hormone-related disorders in women.
68 citations,
January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
67 citations,
December 2013 in “Journal of Biological Chemistry” SCD1 is crucial for skin health and overall energy balance.
59 citations,
August 2021 in “Frontiers in Endocrinology” GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
55 citations,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
37 citations,
October 2021 in “Nutrients” Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.
36 citations,
October 2021 in “Frontiers in Endocrinology” Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
31 citations,
November 2020 in “International journal of molecular sciences” Adipokines affect skin health and could be targeted for treating skin diseases.
26 citations,
July 2012 in “Journal of family planning and reproductive health care” The document says that hirsutism in women usually needs hair removal and hormone treatment to manage symptoms and improve well-being.
20 citations,
April 2021 in “Journal of Womens Health” Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
16 citations,
January 2014 in “Obesity surgery” Vertical sleeve gastrectomy improved metabolism, behavior, and reproduction in obese rats with PCOS.
15 citations,
August 2010 in “Fertility and sterility” Metformin works better for adolescent girls with PCOS who have certain genetic variations.
12 citations,
February 2022 in “International Journal of Clinical Practice” Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.
11 citations,
November 2017 in “Hong Kong Medical Journal” Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.
7 citations,
September 2022 in “Communications biology” Omega-6 fats in certain cells boost male hormone production.
7 citations,
March 2022 in “The FASEB journal” Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
6 citations,
December 2022 in “International Journal of Molecular Sciences” Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.
5 citations,
February 2023 in “Journal of Clinical Medicine” Diagnosing and treating PCOS in teenagers is difficult, and the focus is on lifestyle changes and medication to improve health and prevent future issues.
3 citations,
May 2023 in “Biomedicines” PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.