3 citations
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May 2024 in “Cureus” This study found that LAHR significantly improves the quality of life in the short term for women with PCOS, but underscores a need for further research to develop long-term treatment strategies.
1 citations
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November 2025 in “Clinical Chemistry and Laboratory Medicine (CCLM)” This study developed a new measurement procedure using isotope dilution-liquid chromatography-tandem mass spectrometry for accurate quantification of DHEAS in human serum or plasma, demonstrating high selectivity, sensitivity, and low measurement uncertainty, making it suitable for routine standardization and clinical evaluation.
7 citations
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January 2002 in “Biological Trace Element Research” This study found that children with pituitary dwarfism had higher zinc and copper hair concentrations and lower manganese concentrations compared to healthy children.
2 citations
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January 2020 in “Benha Journal of Applied Sciences” This study found that serum 8-Hydroxydeoxyguanosine levels were significantly higher in alopecia areata patients compared to healthy controls, suggesting its potential as a diagnostic and prognostic biomarker for the condition.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” LIPH mutations cause woolly hair in some Chinese people.
20 citations
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June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” This review summarizes recent research and patents on 17β-HSD3, 17β-HSD5, and 3α-HSD3 inhibitors, suggesting their potential in treating androgen-dependent diseases, but reports no new clinical results.
October 2018 in “International journal of reproduction, contraception, obstetrics and gynecology” In this study, dyslipidemia was found to be prevalent among young adult women with polycystic ovary syndrome in Port Harcourt, Nigeria, particularly characterized by increased triglycerides and decreased HDL-c levels.
This case study reports clinical improvement and complete ulcer resolution in a 29-year-old woman with ANA-negative SLE treated for segmental hyalinizing vasculitis and valvular heart disease.
36 citations
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January 2010 in “Journal of Pediatric Endocrinology and Metabolism” This study identified a novel nonsense mutation in the VDR gene in two patients with hereditary vitamin D resistant rickets and alopecia, leading to resistance to 1,25-dihydroxyvitamin D3.
56 citations
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November 2007 in “Molecular and cellular endocrinology” This study identified enzymes responsible for regulating androgen action in the human prostate, suggesting that inhibiting AKR1C2 or RL-HSD may have therapeutic potential in androgen insufficiency or benign prostatic hyperplasia, respectively.
1 citations
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May 2016 in “Aktuelle Dermatologie” This case study reported that a 34-year-old woman with classic lichen planopilaris achieved disease remission after two months of hydroxychloroquine treatment following ineffective corticosteroid therapy.
March 2026 in “Journal of the American Academy of Dermatology” Hair diameter diversity could improve androgenetic alopecia assessment and treatment planning.
1 citations
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September 2021 in “Cureus” This study found that the rs1128977 SNP in the RXRG gene may be linked to altered clinical characteristics such as higher HDL-cholesterol levels and increased body mass index in individuals with dyslipidemia.
September 2018 in “Fertility and Sterility” In this study, researchers observed that overweight Taiwanese women with PCOS who carry the HSD3B1 1245C allele have a significantly higher risk of developing androgenic alopecia compared to those with the wild-type allele.
October 2018 in “The American journal of gastroenterology” This case study highlights the importance of early detection and management of pembrolizumab-induced hepatitis, suggesting that early steroid treatment could potentially prevent severe complications.
19 citations
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May 2018 in “Molecular Medicine Reports” This study found that miR-339-5p negatively regulates loureirin A-induced differentiation of hair follicle stem cells, potentially impacting skin repair and regeneration by inhibiting the Wnt/β-catenin signaling pathway.
February 2024 in “Clinical, Cosmetic and Investigational Dermatology” This study reports a solid causal relationship between increased serum levels of ApoB, LDL, and VLDL and an elevated risk of androgenic alopecia.
34 citations
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April 2008 in “Journal of the European Academy of Dermatology and Venereology” This study reported that while lichen planus was not significantly linked to hepatitis C virus infection, pruritus, dry skin, and hair loss were more common in HCV patients post-interferon treatment.
2 citations
,
February 2018 in “Journal of bone oncology” This study found that low-dose chemotherapy for solitary bone lesions of Langerhans cell histiocytosis in children led to quicker recovery, higher quality of life at 3 months, and was more cost-effective compared to surgery.
5 citations
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January 2019 in “Skin appendage disorders” This case report emphasizes that lipedematous scalp and lipedematous alopecia are not distinct diseases, highlighting the need to consider reversible causes of alopecia for effective treatment.
December 2025 in “Molecules” This study found that the 15-PGDH inhibitor DPP improved endothelial function in hair-related cells exposed to DHT by reducing oxidative stress and enhancing angiogenic capacity.
October 2025 in “Dermatology Practical & Conceptual” In this study, UVFD and sUVRD techniques revealed distinctive characteristics of GD lesions, suggesting that GD might be more common in younger individuals and females than previously thought, possibly due to underdiagnosis. Incorporating dermatoscopy in exams may help improve GD detection and management.
40 citations
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April 2013 in “Dermato-endocrinology” In this study, researchers observed vitamin D insufficiency in many patients with Alopecia Areata, suggesting its potential role in managing this autoimmune condition.
16 citations
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January 2023 in “Gynecological Endocrinology” In this study, researchers found that unexplained liver damage in PCOS patients may involve iron metabolism and the miR-761-hepcidin/GPX4 axis, suggesting potential therapeutic targets.
14 citations
,
November 2016 in “Lupus” In this retrospective study of adolescents with recalcitrant cutaneous lupus, lenalidomide treatment resulted in complete or near resolution of skin symptoms within 6 months, while allowing for a reduction in prednisone dosage.
August 2025 in “American Journal of Case Reports” In this case report, researchers describe a 13-year-old phenotypic female with 46,XY karyotype, previously misdiagnosed with androgen insensitivity syndrome, who was later identified to have 17-beta-hydroxysteroid dehydrogenase type 3 deficiency, underscoring the importance of genetic and hormonal tests for accurate diagnosis of sex development disorders.
This study found that in an ex vivo model simulating alopecia areata, the DHODH inhibitor farudodstat reduced T-cell proliferation and MHC protein expression in hair follicles, suggesting it may protect against immune privilege collapse without cytotoxic effects.
June 2022 in “Dermatologic Therapy” This case report describes a 14-year-old girl with congenital hypotrichosis who experienced improved hair density and thickness after 3 months of treatment with oral minoxidil.
3 citations
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January 2020 in “JAAD Case Reports” This report describes a patient with symptoms suggestive of both loose anagen hair syndrome and uncombable hair syndrome, adding to previous instances of overlapping features between these conditions.
October 2023 in “Journal of health sciences and medicine :” This study aimed to characterize the dermatological findings in patients with end-stage renal disease undergoing maintenance hemodialysis and explore their relationship with demographic and clinical features, although specific results are not reported in the abstract.