TLDR A girl had two rare hair conditions that helped understand their overlap.
The document described a case of a 10-month-old girl with both loose anagen hair syndrome (LAHS) and uncombable hair syndrome (UHS), characterized by easily extractable anagen hairs and unruly, "spun-glass" hair, respectively. The patient showed patchy hair loss and an unruly hair texture, highlighting the importance of considering multiple syndromes in diagnosis. The coexistence of LAHS and UHS was rare but potentially underreported, and further study was needed to understand any genetic or pathway links between these syndromes.
84 citations
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April 2002 in “Archives of Dermatology” Loose anagen hair syndrome may be caused by keratin gene mutations.
24 citations
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September 1997 in “PubMed” Loose anagen hair can appear at any age and may improve over time.
25 citations
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October 1996 in “Dermatologic Clinics” Loose Anagen Syndrome causes easy-to-pull, thin hair, mainly in young girls, and improves with age.
55 citations
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October 1992 in “Archives of Dermatology” Loose Anagen Hair Syndrome is a hereditary condition causing hair loss in children due to abnormal hair follicles.
101 citations
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July 1985 in “Journal of the American Academy of Dermatology” Biotin improved hair growth and combability in one child with uncombable hair syndrome.
33 citations
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March 2006 in “Seminars in cutaneous medicine and surgery” The document explains how to identify different hair problems using a microscope.
59 citations
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June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
July 2018 in “Elsevier eBooks” The most common cause of hair loss in children is tinea capitis, followed by alopecia areata and telogen effluvium.
February 2021 in “PubMed” A 2-year-old girl had a hair disorder not shared by her identical twin.
7 citations
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November 2013 in “Pediatric and Developmental Pathology” Over half of the children had abnormal hair under a microscope, with many having genetic hair conditions.
