ISIDLB1777 - A Novel Ex Vivo Model of Human Hair Follicle Immune Privilege Collapse Reveals the Potential of Farudodstat, a DHODH Inhibitor, as a Therapeutic for Alopecia Areata Treatment
May 2023
Studysummary This study found that in an ex vivo model simulating alopecia areata, the DHODH inhibitor farudodstat reduced T-cell proliferation and MHC protein expression in hair follicles, suggesting it may protect against immune privilege collapse without cytotoxic effects.
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