TLDR Oral minoxidil and growth factors improved hair density and thickness in a girl with hereditary hair loss.
A 14-year-old girl with hereditary hypotrichosis simplex (HS), a rare form of nonsyndromic alopecia, showed significant improvement in hair density and thickness after 3 months of treatment with oral minoxidil (0.25 mg daily) and growth factors. HS is characterized by progressive scalp hair loss starting in childhood, often leading to near-complete baldness by the third decade. The patient, who had a LIPH gene mutation, experienced positive results, suggesting that oral minoxidil can be an effective treatment for improving hair density and thickness in congenital hypotrichosis.
9 citations,
May 2021 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Topical minoxidil may help treat a rare genetic hair condition with no fully effective treatments yet.
55 citations,
November 2018 in “American journal of human genetics” Mutations in the LSS gene cause a rare type of hereditary hair loss.
33 citations,
June 2016 in “Pediatric Dermatology” Some congenital hair disorders improve in childhood or with treatments like minoxidil and retinoids, while others like Netherton syndrome and trichothiodystrophy have a poor prognosis.
1 citations,
August 2022 in “JAAD case reports” Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.
June 2022 in “Dermatologic Therapy” Oral minoxidil and growth factors improved hair density and thickness in a girl with hereditary hair loss.
February 2020 in “The Pharmaceutical Society of Japan” 
3 citations,
January 2018 A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.
14 citations,
January 2015 in “Skin appendage disorders” Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.
July 2013 in “DeckerMed Medicine” The document's conclusion cannot be provided because the document is not readable or understandable.
1 citations,
September 2002 in “PubMed” Minoxidil helps stimulate hair growth and reduce hair loss in women with androgenic alopecia.
