7 citations
,
December 2011 in “Annals of anatomy” This study found that involucrin likely plays a key role in forming the cornified material of the medulla and inner root sheath of human hair, contributing to its mechanical strength.
April 2009 in “The FASEB Journal” This study demonstrated that a keratin gel promotes nerve regeneration across critical defects in rabbit models, showing improved nerve conduction and muscle action potential compared to control treatments.
September 2008 in “Acta Ophthalmologica” This study found that murine vibrissa hair follicle stem cells can differentiate into corneal epithelial-like cells in vitro when cultured with limbus-specific microenvironmental factors.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This research found that the microtubule catastrophe factor KIF18B plays a crucial role in promoting spindle orientation in keratinocytes, linking this process to cell fate decisions during hair follicle morphogenesis.
82 citations
,
January 2006 in “International review of cytology” Vertebrate skin evolved to be more specialized and complex, especially in land animals.
4 citations
,
January 2020
438 citations
,
October 2010 in “Oncogene” This review discusses the role of keratins in epithelial cell stress protection and cancer, highlighting their potential as multifunctional regulators and diagnostic markers, without presenting new research findings.
22 citations
,
October 1996 in “Dermatologic clinics” This review summarizes recent advances in understanding intermediate filament structure and their implications for pathological mutations and human diseases, but it reports no new experimental results.
18 citations
,
March 2009 in “Experimental Dermatology” This study suggests that pilomatricoma can differentiate towards various hair follicle structures, including hair matrix, hair cortex, follicular infundibulum, outer root sheath, and hair bulge.
5 citations
,
June 2008 in “British Journal of Dermatology” 1 citations
,
December 1997 in “Archives of dermatology” This report describes a case of trichostasis spinulosa, a condition with pruritic, black papules on the face caused by keratotic plugs with embedded vellus hairs.
18 citations
,
November 2005 in “European Journal of Cell Biology” Keratin gene clusters in humans and marsupials are similarly organized.
57 citations
,
January 1987 in “Journal of Biological Chemistry” This study identified and sequenced several keratin cDNA clones showing distinct expression patterns in mouse epithelia, with in situ hybridization highlighting differences in keratin distribution between normal and hyperproliferative tissues.
6 citations
,
July 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This case report describes a successful eyebrow reconstruction using hair follicle micrografts in a patient with dormant keratosis pilaris atrophicans, demonstrating potential for this technique in similar conditions.
3 citations
,
March 2021 in “Indonesia Medicus Veterinus” This case report describes successful treatment of anaplasmosis in a Kintamani mix dog with doxycycline, ivermectin, vetadryl, and Livron b-plex, leading to improved activity, hair growth, appetite, and tick eradication.
49 citations
,
July 2006 in “British Journal of Dermatology” This study observed that calcifying epithelioma of Malherbe is composed of tumor cells that differentiate into both hair cortex and outer root sheath, supporting its hair follicle origin.
28 citations
,
April 1996 in “Cell biology international” This review discusses changes in keratin structure or gene expression that result in various skin disorders and reports no new clinical findings.
16 citations
,
October 2022 in “Biomimetics” This study found that Trichosanthes kirilowii extract significantly enhances keratinocyte proliferation and wound healing in vitro and in vivo, suggesting its potential as a wound-healing component.
26 citations
,
August 2007 in “Annals of Anatomy - Anatomischer Anzeiger” Feathers become harder as they develop due to a change in keratin type.
187 citations
,
May 1988 in “Differentiation” This study found that trichocytic cytokeratins, typically found in hair, are also present in nails, filiform papillae of the tongue, and the epithelial reticulum of the thymus.
12 citations
,
June 2013 in “International Journal of Dermatology” This study found that different types of seborrheic keratosis demonstrate diverse differentiation patterns, highlighting its undifferentiated and hyperproliferative state with varying keratinization directions.
9 citations
,
February 2016 in “Anatomical Science International” Hair proteins change location and structure as hair cells mature.
1 citations
,
January 2019 in “Pan African Medical Journal” This case report describes a 30-year-old woman with keratosis pilaris treated with emollients and keratolytics, resulting in slight improvement.
56 citations
,
January 1977 90 citations
,
July 1993 in “Journal of Investigative Dermatology” 18 citations
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November 1989 in “Clinical and experimental dermatology” This case report describes a 5-year-old girl with an extensive Microsporum canis scalp infection, highlighting griseofulvin as the preferred treatment and noting corticosteroids' benefit in severe inflammatory cases.
November 2016 in “Oncology Letters” This study suggests that the expression patterns of keratin and filaggrin indicate milia may originate from the outermost cells of the hair bulge in the outer root sheath.
21 citations
,
June 2003 in “Journal of Morphology” This study suggests that the epidermis of monotremes and marsupials exhibits a more primitive pattern of protein distribution compared to eutherian mammals, with differences in loricrin distribution and keratinocyte maturation.
March 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that both epithelial and hair keratins are expressed in beard hair medulla cells, exhibiting unique patterns and interactions distinct from other hair follicle and epithelial cells.
May 2002 in “Journal of Investigative Dermatology” New findings on hair keratin, wound healing, and skin blistering were presented.