In This Issue
May 2002
in “
Journal of Investigative Dermatology
”
TLDR New findings on hair keratin, wound healing, and skin blistering were presented.
The document discussed three main studies. The first study by Langbein et al. characterized a novel human inner root sheath (IRS) keratin, hK6irs1, in the hair follicle, suggesting its role in maintaining a tight cell layer and its potential link to hair diseases like alopecia. The second study by Mazzalupo et al. introduced an ex vivo assay to assess keratinocyte wound healing, highlighting the importance of the dermal extracellular matrix in keratinocyte behavior. The third study by Amagai et al. explored the role of staphylococcal exfoliative toxin B in cleaving desmoglein 1, contributing to blister formation in staphylococcal scalded skin syndrome, similar to exfoliative toxin A.