138 citations
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March 2007 in “Experimental cell research” This review discusses hair keratins and hair follicle-specific epithelial keratins and their association with inherited hair disorders, reporting no new clinical results.
This review suggests that the inner root sheath of human hair follicles may have broader regulatory roles beyond structural support, potentially impacting processes like folliculogenesis, anagen phase regulation, and immunomodulation.
January 2026 in “International Ayurvedic Medical Journal” This case report observed significant improvement in a 23-year-old male with Khalitya/Androgenetic alopecia after undergoing Ayurvedic management.
71 citations
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August 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This study revealed that human keratin-associated protein genes are expressed in specific patterns in hair fiber regions and vary in size, with some variations distinct across different populations.
June 2024 in “British Journal of Dermatology” This article presents a family case study of dermatopathia pigmentosa reticularis linked to a specific KRT14 gene variant, detailing symptoms and stressing the importance of molecular diagnosis for management.
9 citations
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February 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This review discusses the complexity and genetic organization of human keratin gene clusters and addresses the ongoing need for an updated unified naming system; it reports no new clinical results.
2 citations
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September 2002 in “Dermatologic Surgery” This study describes how arrector pili muscles form a single muscular structure shared by all hair follicles within a follicular unit at the isthmus level in scalp skin.
April 2025 in “The Journal of Dermatology” This study provides initial insights into the use of JAK inhibitors for CTCL, reporting some cases of symptom improvement, but highlights the need for further research on their association with CTCL development and safety.
2 citations
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June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study demonstrates that in vivo live imaging reveals how distinct stem cell activities in the limbal niche coordinate corneal regeneration.
January 2011 in “Anhui nongye kexue” This study reports that the recombinant expression vector pcDNA3.1-KK demonstrates specific expression in the skin of newborn mice.
This review discusses the unique characteristics and possible pathophysiology of spiny keratoderma, reporting no new clinical results, but suggests that some therapies might alleviate symptoms.
46 citations
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November 1998 in “Experimental Cell Research” This study found that K15 is variably expressed in sheep and mouse hair follicles, with specific patterns suggesting a role in the early stages of keratinocyte differentiation.
March 2026 in “Virulence” This narrative review suggests that intermediate filaments like vimentin and keratin play a significant role in various stages of viral infection, presenting potential antiviral intervention targets.
January 2024 in “Dermatologic Surgery” This abstract pertains to a dermatology-related academic profile without reporting any specific study findings. Results or research details are not provided.
This study analyzed inner root sheath-specific genes in Tan sheep during various growth stages, finding peak expression at birth. The pattern of genes KRT71, KRT72, and TCHH is consistent with wool crimp, potentially influencing wool morphology.
January 2016 in “Frontiers in Bioengineering and Biotechnology” In this study, a porous keratin hydrogel derived from wool hair demonstrated strong mechanical properties and supported the growth of various animal cells, indicating potential as a scaffold in tissue engineering.
September 2020 in “Oral surgery, oral medicine, oral pathology and oral radiology” This case report describes a pilomatricoma in a 21-year-old woman, highlighting the diagnostic process and illustrating the potential for intraoral surgical access to minimize scarring.
152 citations
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April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study presents evidence that keratitis–ichthyosis–deafness syndrome is caused by a mutation in the connexin 26 gene, expanding the gene's known involvement in various disorders.
1 citations
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July 2025 in “JCI Insight” This study found that Krox20 marks a diverse stem cell population in mouse hair follicles, which significantly contributes to the interfollicular epidermis and regulates epidermal homeostasis.
65 citations
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September 2014 in “BMC genomics” This research found that variations in the KRTAP gene family are likely responsible for the diverse hair phenotypes seen among mammals, influenced by gene repertoire differences, expression, and evolutionary factors.
1 citations
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August 2021 This case report describes a 10-year-old patient with a rare trichilemmal cyst in the cervical region, highlighting the importance of close monitoring due to potential risks of malignancy.
23 citations
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January 1986 This review discusses the chemical stability of protein envelopes found in the epidermis and other stratified squamous epithelia, but reports no new clinical results.
January 2026 in “Updates in clinical dermatology”
November 2024 in “NeoReviews” Pallister-Killian Syndrome is a complex genetic disorder requiring coordinated care and genetic counseling.
70 citations
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January 2014 in “International review of cell and molecular biology” This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.
248 citations
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April 1988 in “Differentiation” In this study, researchers observed that trichocytic and epithelial cytokeratins have distinct expression patterns within various human and bovine hair follicle cells, contributing to understanding hair follicle development and growth.
37 citations
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May 1998 in “Journal of Dermatological Science” Basal cell carcinoma shows keratin patterns similar to undifferentiated hair follicle cells.
1 citations
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July 2018 in “JAMA dermatology” This abstract contains navigation and subscription information for JAMA Dermatology and reports no new clinical findings.
January 2009 in “Elsevier eBooks” 13 citations
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January 2001 in “Pediatric dermatology” This study reports pseudopili annulati in a dark-haired Chinese girl, identifying the unique appearance and structural characteristics of her hair without finding abnormalities in the cuticle and cortex.