3 citations
,
November 2018 in “Curēus” This article reviews the occurrence of ectopic sebaceous glands in hair follicle matrix during hair embryogenesis and reports no new clinical results, indicating unknown pathogenesis and clinical implications.
32 citations
,
January 2017 in “PLoS ONE” This study found that adiponectin significantly enhanced lipid production in human sebaceous glands and may be a potential target for treating conditions with reduced sebum production.
1 citations
,
January 2009 In this case report, a 25-year-old man with nevus comedonicus showed no improvement from keratolytics and topical tretinoin, but had success with surgical excision of the lesions.
January 2005 in “Journal of Cutaneous Pathology” This report presents the first known case of a proliferating hybrid cyst containing both epidermoid and trichilemmal components on the scrotum of a 44-year-old man.
2 citations
,
November 2003 in “Humana Press eBooks” This article explains the significance of culturing the pilosebaceous unit for studying related diseases and skin epithelial stem cells, but it reports no new findings.
4 citations
,
January 2023 in “Veterinary Sciences” This study found that applications of a shampoo and mousse containing plant extracts improved coat quality in dogs with a chronic keratinisation disorder without affecting skin hydration or hair lipids over the study period.
195 citations
,
December 2009 in “Journal of Investigative Dermatology” This study found that sebum free fatty acids may enhance the antibacterial defense of human sebaceous glands by upregulating the expression of the antimicrobial peptide hBD-2, potentially aiding in acne treatment.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study indicates that MPZL3 negatively regulates sebaceous gland size in mice by controlling sebocyte proliferation, with implications for disorders like acne and psoriasis.
1 citations
,
January 2019 in “Pan African Medical Journal” This case report describes a 30-year-old woman with keratosis pilaris treated with emollients and keratolytics, resulting in slight improvement.
2 citations
,
June 1989 in “Archives of Dermatology” This case report describes a 65-year-old man's trichofolliculoma, a hair follicle-origin tumor, which appeared as a persistent cheek pore extrusion and was removed at the patient's request.
28 citations
,
January 1986 in “International Journal of Dermatology” This case study describes a pregnant woman who developed a pruritic rash with follicular lesions containing yeast-like organisms, resistant to conventional acne treatments.
205 citations
,
July 2009 in “Journal of Dermatological Science” This review discusses gender-linked skin differences, such as hormone metabolism and sebum production, and reports no new findings; it suggests these insights might inform male-specific dermatological treatments or cosmetic products.
36 citations
,
January 2023 in “Skin Appendage Disorders” This review discusses the etiology, pathophysiology, trichoscopic characteristics, differential diagnoses, and treatment options for scalp seborrheic dermatitis, without providing new clinical findings.
198 citations
,
January 1998 in “Dermatology” This review discusses human sebocyte in vitro models for studying sebaceous gland function and control but reports no new clinical results, highlighting hormonal effects and the impact of retinoids on sebocyte activity.
7 citations
,
March 1993 in “International Journal of Oncology” This study found that the keratin expression in basal cell carcinoma resembles that of the pilosebaceous apparatus, with uniform presence of certain keratins in all cases.
This review provides an overview of the etiology, presentation, and diagnosis of steatocystomas, including subtypes and complications, while detailing their history, epidemiology, and management strategies.
13 citations
,
June 2018 in “Dermatopathology” This classification proposal introduces a novel system for categorizing cutaneous adnexal cysts based on their origin in the folliculosebaceous unit and sweat glands, aiming to simplify and enhance understanding of these skin lesions.
48 citations
,
August 2018 in “Nature Communications” This study found that JunB, a transcription factor, is crucial for maintaining epidermal-pilosebaceous stem cell homeostasis by regulating progenitor cell behavior and preventing sebaceous gland dysfunction.
7 citations
,
January 1989 in “Archives of Dermatological Research” The side gland of Suncus murinus is a good model for studying human sebaceous glands.
62 citations
,
September 2014 in “PLoS ONE” This study identified distinct human and bacterial protein profiles in sebaceous follicular casts, with acne samples showing proteins linked to inflammation and normal samples showing proteins involved in stress protection.
September 2022 in “Medical Mycology” This study found that patients with androgenic alopecia exhibited higher levels of Malassezia colonization and altered sebum composition compared to individuals without AGA.
2 citations
,
May 1991 in “PubMed” This article reviews naevus comedonicus, highlighting potential treatments like retinoic acid application and surgical intervention, but reports no new clinical findings.
18 citations
,
December 1992 in “Journal of Cutaneous Pathology” This study observed that lectin-binding patterns in skin appendage tumors reveal differences in sweat gland tumors compared to normal tissues, but pilosebaceous tumors maintained a similar lectin-binding pattern to their corresponding normal structures.
6 citations
,
January 2001 in “Cambridge University Press eBooks” This review discusses how androgen excess in polycystic ovary syndrome can lead to hirsutism, seborrhea, and worsen conditions like androgenetic alopecia and acne, but includes no new research findings.
January 2024 in “Jurnal Ilmu Kesehatan Hewan” In this veterinary case report, a mixed breed dog with Malassezia dermatitis showed significant improvement and hair regrowth after 28 days of treatment with ketoconazole and other supportive therapies.
26 citations
,
March 2018 in “Experimental Dermatology” This article argues that prolactin may have a role in sebaceous gland function and suggests it could be a potential target for treating skin conditions, but reports no new clinical findings.
13 citations
,
August 1999 in “Journal of Investigative Dermatology” This study found that bikunin is expressed in human keratinocytes and may play a role in regulating keratinocyte function during mitosis or inflammation.
In this study assessing post-menopausal Asian women, distinct shifts in Malassezia species prevalence on the skin were linked to increased inflammation and impaired skin barrier function, potentially driving disorders like psoriasis and seborrheic dermatitis.
2 citations
,
September 2010 in “Acta Ophthalmologica” The study concluded that all parts of the normal human Meibomian gland ductal system show signs of early keratinisation, supporting the idea that these glands are akin to "hair follicles without a hair shaft.
March 2021 in “Revista da Associação Médica Brasileira”