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Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Different types of skin cells play specific roles in development, healing, and cancer.

PGD2 stops hair growth and is higher in bald men with AGA.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Blocking JAK-STAT signaling can lead to hair growth.

Aging causes skin stem cells to work less effectively.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.