A Group of Type I Keratin Genes on Human Chromosome 17: Characterization and Expression

    February 1988 in “ Molecular and Cellular Biology
    Marjorie Rosenberg, Amlan RayChaudhury, Thomas B. Shows, Michelle M. Le Beau, Elaine Fuchs
    TLDR Only one of the two K16 genes on chromosome 17 makes a functional protein for keratin filaments.
    The study characterized a group of type I keratin genes located on human chromosome 17, focusing on their structure and expression patterns. The researchers identified several keratin genes and analyzed their sequences to understand their organization and regulation. The findings provided insights into the complexity of the keratin gene family and their potential roles in cellular processes. This research contributed to the broader understanding of keratin gene expression and its implications in human biology.
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