January 2019 in “Springer eBooks” Micrografts are useful for healing wounds, regenerating bone and periodontal tissues, and improving hair transplantation outcomes.
November 2005 in “Hair transplant forum international” This abstract describes the use of different gauge needles for follicular unit transplantation but does not report any new research findings.
10 citations
,
September 2024 in “Journal of Nanobiotechnology” This study developed an antimicrobial microneedle patch for delivering apoptotic vesicles to treat infected wounds, which was found to effectively reduce bacterial growth and accelerate scarless healing, including the rapid formation of mature hair follicles in just 8 days, a previously unreported early outcome.
January 2018 in “Journal of cosmetology & trichology” This study describes the use of automatic Biofibre® hair implants as a surgical technique for hair restoration, offering immediate aesthetic results for men and women with hair loss or thinning, provided certain conditions for success are met.
52 citations
,
October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
4 citations
,
April 2024 in “Cellular and Molecular Biology” In this study, injectable platelet-rich fibrin (i-PRF) was found to enhance the proliferative, migratory, and hair-inducing abilities of dermal papilla cells more effectively than platelet-rich plasma through the TGF-β/Smad pathway.
20 citations
,
January 1979 in “JAMA” In this study, fiber implantation for pattern baldness was deemed ineffective and resulted in complications such as infection, scarring, and permanent hair loss, making it an unacceptable treatment option.
January 2008 in “Chinese Journal of Aesthetic and Plastic Surgery” This study found that an injectable material derived from hair shows good biocompatibility and promotes dermal thickness in pigs, suggesting potential as a new soft tissue filling agent.
1 citations
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April 1995 in “Annals of Plastic Surgery” This study describes the Mercedes incision technique, which may improve hair transplant results by reducing graft compression and row cropping, leading to a more natural appearance.
9 citations
,
March 2018 in “Plastic and Aesthetic Research” This article introduces direct hair implantation, a modification of follicular unit extraction, using unique pens, but reports no clinical results.
9 citations
,
January 2020 in “IEEE Access” This study reports that a robotic and AI-based system successfully analyzes FUE hair transplant procedures, aiding surgeons in planning and assessing operation success through detailed pre-op and post-op evaluations.
69 citations
,
October 2013 in “Tissue Engineering Part A” This study found that using a keratin hydrogel scaffold as a filler in collagen nerve conduits significantly improved nerve regeneration and motor recovery in Macaca fascicularis monkeys compared to saline.
July 2020 in “CRS 2020 Virtual Annual Meeting” This study found that the newly developed microarray patches for intradermal delivery of finasteride showed high drug content and significantly improved skin deposition compared to existing methods.
24 citations
,
May 1995 in “Journal of Adolescent Health” This study of Black and Hispanic inner-city teens found that Norplant retention rates were 71% at one year and 62% at two years, with a history of induced abortion predicting higher continuation.
4 citations
,
May 2005 in “Seminars in Plastic Surgery” This article discusses the development and refinement of the hair-micrografting technique in cosmetic surgery and reports no new clinical results.
August 2019 in “Journal of The American Academy of Dermatology” This article discusses the premade slit method in hair restoration surgery, emphasizing the importance of a tailored depth control instrument for optimal follicle implantation, but provides no new clinical results.
October 2022 in “Hair Transplantation” This chapter reviews the critical importance of the follicle placement process in hair transplantation but presents no new clinical findings.
15 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This article discusses follicular cell implantation as a potential solution for hair restoration limitations, but notes inconsistencies and challenges in human applications, reporting no new clinical results.
January 2025 in “Zagazig University Medical Journal” This study found that nanofat injection before hair transplant may improve the survival of hair grafts in patients with secondary cicatricial alopecia.
26 citations
,
July 2023 in “International Journal of Nanomedicine” The researchers suggest that combining microneedle technology with nanocarriers could enhance drug delivery systems for treating central neurological diseases due to nanoparticles' ability to prolong blood circulation time and improve brain targeting.
July 2003 in “Hair transplant forum international” This article discusses needle-stick injury risks in hair restoration practices and reports no new research findings; the authors emphasize the potential for disease transmission and safety concerns.
2 citations
,
October 2021 in “Experimental Cell Research” This study found that injectable platelet-rich fibrin (i-PRF) enhances hair follicle regeneration in vitro by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity, with varying effects depending on concentration.
3 citations
,
February 2002 in “Dermatologic Surgery” Using a handheld massage device during hair transplant significantly reduces pain for most patients.
192 citations
,
April 2019 in “ACS nano” In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this article, researchers describe a novel FUE device designed to enhance follicular unit excision surgery by minimizing follicular injury and improving ergonomics with features such as Bluetooth functionality, fingertip touch sensors, and automated operation.
This study found that an injectable hair material showed good biocompatibility in micropigs and effectively promoted dermal thickening, suggesting its potential as a new soft tissue filler.
10 citations
,
January 1997 in “Scandinavian journal of plastic and reconstructive surgery and hand surgery” This study found that using a multibladed knife during hair transplantation surgery enhanced the rate of minigraft preparation and produced more uniformly sized grafts compared to traditional techniques.
September 2025 in “International Society of Hair Restoration Surgery” This study introduces a new method using printable templates to create standardized and optimized hairlines in male hair transplantation, reportedly improving surgical precision and enabling consistent, aesthetically pleasing outcomes.
March 2024 in “ACS Applied Materials & Interfaces” This study developed a delivery platform using hyaluronic acid-based dissolvable microneedles with nanoliposomes containing kopexil and kopyrrol, which showed improved hair regeneration for treating androgenetic alopecia in vivo at lower dosages compared to minoxidil.
21 citations
,
October 2025 in “Advanced Materials” This study found that a newly created biomimetic microneedle platform effectively expedited wound repair in diabetic animal models by reducing inflammation, enhancing angiogenesis, and promoting skin regeneration through targeted drug delivery and immune response modification.