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390-420 / 1000+ resultsresearch Ontogeny and regional variability of keratin 2e (K2e) in developing human fetal skin: a unique spatial and temporal pattern of keratin expression in development
This study shows that keratin 2e exhibits distinct temporal and regional expression patterns in fetal epidermis, suggesting different regulatory and functional roles from other epidermal keratins.
research Disruption of tubular Flcn expression as a mouse model for renal tumor induction
This study developed a kidney-specific knockout mouse model lacking the Flcn gene, which recapitulates human Birt-Hogg-Dubé kidney tumorigenesis and shows that mTOR pathway inhibition with rapamycin can suppress tumor growth.
research Emerging role of ILK and ELMO2 in the integration of adhesion and migration pathways
This study found that ILK/ELMO2 complexes in epidermal keratinocytes are selectively activated by epidermal growth factor to induce cell migration, unlike with other growth factors.
research ORLANDO LIVE SURGERY WORKSHOP XIV: ADVANCING THE INDUSTRY OF HAIR RESTORATION APRIL 3-5 2008 ORLANDO
This event overview highlights the dual focus on education and friendship among participants, but it reports no new research findings.
research 52B Follicular unit excision (FUE)terminology Follicular Unit Excision Terminology And Overview
This article discusses the establishment and global adoption of standardized terminology for follicular unit excision (FUE) by the ISHRS, which aids effective communication among hair restoration practitioners.
research Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency
This study reports that a widespread founder SERPINB7 mutation underlies Nagashima-type palmoplantar keratosis, which is a common form of palmoplantar keratosis in Asian populations.
research E.L.F. sqare waves: a new therapy for androgenetic alopecia?
New therapy helps treat hair loss.
research Fibroblast bioelectric signaling drives hair growth
Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.
research Discoid lupus alopecia complicated by frontal fibrosing alopecia on a background of androgenetic alopecia
Woman has discoid lupus, frontal fibrosing, and androgenetic alopecia.
research Runx1 transcription factor is involved in the regulation of KAP5 gene expression in human hair follicles
Runx1 helps control the KAP5 gene in human hair follicles.
research Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge
The K15 promoter effectively targets stem cells in the hair follicle bulge.
research Concerted gene duplications in the two keratin gene families
research Investigation of human hair fibers using lateral force microscopy
Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.
research Characterization of new stem/progenitor cells in skin appendages
In this study, researchers identified slow cycling label retaining cells in nail and sweat gland appendages, showing stem cell characteristics similar to hair follicles but with distinct features.
research Non-histone Methylation of SET7/9 and its Biological Functions
This review examines the role of SET7/9 in non-histone methylation and its implications in various diseases, including cancer, but presents no new clinical results.
research Effect of FOLFOX6 chemotherapy on serum VEGF expression in advanced colorectal cancer patients
This study found that FOLFOX6 chemotherapy significantly decreased serum VEGF and CRP levels in advanced colorectal cancer patients, improved their quality of life as measured by KPS scores, and demonstrated a high overall therapeutic efficacy of 82.72% with manageable side effects.
research BH04 A hair-raising complication: de novo frontal fibrosing alopecia after transplantation
This study presents cases suggesting that hair transplantation may trigger de novo frontal fibrosing alopecia in some patients, highlighting a potential association worth considering as cosmetic hair procedures become more common.
research lncRNA2919 Suppresses Rabbit Dermal Papilla Cell Proliferation via trans-Regulatory Actions
This study found that the lncRNA lncRNA2919 is involved in hair follicle regeneration by downregulating growth-related genes, inhibiting cell proliferation, and promoting apoptosis in rabbit dermal papilla cells.
research Long Hair FUE and the Donor Area Preview
This abstract reviews the evolution of hair restoration techniques, from 19th-century surgical scalp flaps to modern FUE and FUT methods, without providing new clinical findings.
research 1377 Decoding frontal fibrosing alopecia and lichen planopilaris: Macrophages hold the key?
This study suggests that macrophages play a more substantial role in the pathogenesis of Lichen planopilaris compared to Frontal fibrosing alopecia, as indicated by increased CD68+ cells in Lichen planopilaris.
research Lactoferrin promotes hair growth in mice and increases dermal papilla cell proliferation through Erk/Akt and Wnt signaling pathways
This study found that bovine lactoferrin promotes hair growth in mice by enhancing dermal papilla cell proliferation through the Erk/Akt and Wnt signaling pathways.
research LGBTQ+ STEM @UCL Network: Fostering an inclusive and visible community
This abstract contains only graphical design information and does not report any research findings or conclusions.
research ANTI‐HAIR KERATIN MONOCLONAL ANTIBODY (HKN‐2)
This study identified a monoclonal antibody, HKN-2, that recognizes specific cells in human skin and may indicate a common antigenic determinant between hair and other skin epithelial tissues.
research 1397 LSD1 is critical for epidermal development and skin barrier formation
This study found that LSD1 is crucial for embryonic skin barrier formation in mice, revealing its significant role in epidermal development and suggesting its potential as a target in skin diseases with barrier defects.
research Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-associated Protein (KAP) Genes on Chromosome 21q22.1
This study identified a domain on human chromosome 21q22.1 containing various high glycine-tyrosine and high sulfur keratin-associated protein genes, revealing their diverse expression in hair-forming cells.
research Hair Restoration by FUE and BHT – Baldness treatment with beard hair transplantation in Los Angeles
research A Novel Follicular Unit Excision Device for All-Purpose Hair Graft Harvesting
This study describes a novel FUE device that may perform successfully across various patient scenarios, adapting to differences in skin firmness, thickness, and hair curliness.
research Frontal fibrosing alopecia versus lichen planopilaris: a clinicopathological study
This study found that frontal fibrosing alopecia and lichen planopilaris have similar histopathological features, but FFA exhibits more prominent apoptosis and less inflammation with spared interfollicular epidermis.
research Transcriptome analysis of frontal fibrosis alopecia revealed involvement of immune cells and ferroptosis
The researchers in this study identified molecular mechanisms involved in frontal fibrosis alopecia, highlighting immune response and fatty acid metabolism, and developed a four-gene diagnostic model showing high accuracy in distinguishing affected individuals from controls.