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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Transplant success has improved with better immunosuppressive drugs and donor matching.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Early detection of specific skin lesions can help identify Birt-Hogg-Dube syndrome and prevent serious complications.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Chinese patients with systemic lupus erythematosus commonly experience oral ulcers, arthritis, alopecia, skin rash, and nephritis.

Antiviral medication valganciclovir may improve skin and hair in Trichodysplasia Spinulosa patients.

Balding and low testosterone increase risk of urinary stones.

A woman with anorexia developed gout from self-induced vomiting.

Bardet-Biedl syndrome may include under-recognized skin problems related to its metabolic disturbances.

Mycophenolate mofetil is effective for treating severe lupus nephritis in children.

About 8% of people with systemic lupus erythematosus have chronic scarring alopecia, with certain symptoms and positive antibodies increasing the risk, while immunosuppressants may lower it.

Vitamin A deficiency changes cattle hair structure, while pregnancy may improve it, suggesting hair can indicate cattle health.

A scalp biopsy revealed systemic amyloidosis in a woman who initially seemed to have a common hair loss condition.

Older men with scalp wounds had long-term healing problems after using imiquimod or diclofenac for skin cancer prevention.

A woman with undifferentiated connective tissue disease was diagnosed with renal amyloidosis and carpal tunnel syndrome.

The patient had complex urinary tract issues and ambiguous genitalia, with physical features suggesting a hormonal imbalance.

The woman was diagnosed with systemic lupus erythematosus (SLE) after initial misdiagnosis and improved with proper treatment.

Genetic testing for EGFR mutations is crucial in similar cases.

Azathioprine can cause severe blood issues and hair loss, needing careful monitoring and possible discontinuation.

A hemodialysis patient's hair loss was caused by the drug tinzaparin but stopped after switching to a different drug.

Medicare Part D causes significant coverage and cost issues for end-stage renal disease patients.

Cultural awareness in healthcare improves patient care and relationships.

Long-term diabetes is linked to lower prostate cancer risk.

Higher BMI is linked to a lower risk of non-aggressive prostate cancer and a higher risk of aggressive prostate cancer.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Four-amino acid part makes enzyme sensitive to finasteride.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.