TLDR Resveratrol improved menstrual regularity and reduced hair loss in women with PCOS.
This randomized trial investigated the effects of resveratrol on menstrual dysfunction, hyperandrogenism, and metabolic profile in women with PCOS. Seventy-eight women aged 18-40 were assigned to either a resveratrol (1000 mg) or placebo group for 3 months. The study found that resveratrol significantly improved menstrual regularity (76.47% vs. 51.61%; p = 0.03) and reduced hair loss (32.10% vs. 68.00%; p = 0.009) compared to placebo. However, there were no significant changes in androgen levels, insulin, lipid profiles, or other metabolic parameters. Resveratrol did not affect thyroid, liver, or kidney functions but had a negative impact on body composition without altering weight.
12 citations
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December 2012 in “Current Drug Targets”
The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
4025 citations
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December 2003 in “Human Reproduction”
The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
Female with PCOS experiences receding and thinning hair, wants dutasteride instead of spironolactone. Discusses desire to reduce DHT without losing libido.
A female with PCOS and androgenetic alopecia is starting treatment with oral Minoxidil, topical Minoxidil 5% with finasteride, and plans to add mesotherapy. She previously tried anti-androgenic contraceptive pills but couldn't tolerate them and is using Myo Inositol for weight management.
A 20-year-old female with PCOS is experiencing hairloss and excessive facial hair. She is using ketoconazole and caffeine shampoos, microneedling, and considering anti-androgens like finasteride, but is cautious about minoxidil due to facial hair concerns.
OP shares their experience with PCOS-related hairloss, highlighting that addressing vitamin D and ferritin deficiencies, managing hormones with spironolactone, and using gentle hair care products helped improve their condition. They advise against relying on "miracle" hair oils and emphasize the importance of medical evaluation and a combined approach to treatment.
A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.
The user experienced severe hair shedding from RU58841 and recovered by stopping its use and starting treatments including Minoxidil, Rosemary Verbenone, Stemoxydine, Aminexil, copper peptide serum, and specific shampoos. They also consistently used oral Finasteride and plan to try Minoxidil 10%.
3 citations
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January 2012 in “Hanyang Medical Reviews”
The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.
